N-(oxolan-2-ylmethyl)-N-(pyridin-2-ylmethyl)pyrazolo[1,5-a]pyridine-7-carboxamide

• ChemBase ID: 850792
• Molecular Formular: C19H20N4O2
• Molecular Mass: 336.3877
• Monoisotopic Mass: 336.1586259
• SMILES: c1(n2c(ccn2)ccc1)C(=O)N(Cc1ncccc1)CC1OCCC1
• Canonical SMILES: O=C(c1cccc2n1ncc2)N(Cc1ccccn1)CC1CCCO1
• InChI: InChI=1S/C19H20N4O2/c24-19(18-8-3-6-16-9-11-21-23(16)18)22(14-17-7-4-12-25-17)13-15-5-1-2-10-20-15/h1-3,5-6,8-11,17H,4,7,12-14H2
• InChIKey: FGCWSYZRGLWWRC-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: N-(oxolan-2-ylmethyl)-N-(pyridin-2-ylmethyl)pyrazolo[1,5-a]pyridine-7-carboxamide
• IUPAC Traditional name: N-(oxolan-2-ylmethyl)-N-(pyridin-2-ylmethyl)pyrazolo[1,5-a]pyridine-7-carboxamide
• Synonyms: N-(pyridin-2-ylmethyl)-N-(tetrahydrofuran-2-ylmethyl)pyrazolo[1,5-a]pyridine-7-carboxamide

CALCULATED PROPERTIES

JChem

• H Acceptors: 4
• H Donor: 0
• LogD (pH = 5.5): 1.7103126
• LogD (pH = 7.4): 1.7278101
• Log P: 1.7280382
• Molar Refractivity: 104.9154 cm^3
• Polarizability: 36.493137 Å^3
• Polar Surface Area: 59.73 Å^2
• Rotatable Bonds: 5
• Lipinski's Rule of Five: true

供应商提供(Chembridge)

• H Acceptors: 4
• H Donor: 0
• Log P: 0.24
• LOG S: -1.87
• Polar Surface Area: 59.73 Å^2
• Rotatable Bonds: 5