NAMES AND DATABASE IDS
NAMES AND DATABASE IDS
Names Database IDs
IUPAC name
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[2-(diphenylmethoxy)ethyl]dimethylamine hydrochloride
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IUPAC Traditional name
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diphenhydramine hydrochloride
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Synonyms
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Benadryl
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Dimedrol
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Daedalon
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Diphenhydramine hcl
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[2-(diphenylmethoxy)ethyl]dimethylamine hydrochloride
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Diphenhydramine hydrochloride
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N-[2-Diphenylmethoxyethyl]-N,N-dimethylamine
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DIPHENHYDRAMINE HYDROCHLORIDE
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2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride
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N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride
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2-二苯甲氧基-N,N-二甲基乙胺 盐酸盐
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N,N-二甲基-2-(二苯甲氧基)乙胺 盐酸盐
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苯海拉明 盐酸盐
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CAS Number
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EC Number
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MDL Number
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PubChem SID
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PubChem CID
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DATA SOURCES
DATA SOURCES
All Sources Commercial Sources Non-commercial Sources
CALCULATED PROPERTIES
CALCULATED PROPERTIES
JChem
H Acceptors
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2
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H Donor
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0
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LogD (pH = 5.5)
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0.52368176
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LogD (pH = 7.4)
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2.174247
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Log P
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3.6519072
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Molar Refractivity
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79.927 cm3
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Polarizability
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31.40543 Å3
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Polar Surface Area
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12.47 Å2
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Rotatable Bonds
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6
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Lipinski's Rule of Five
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true
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DETAILS
DETAILS
MP Biomedicals
Selleck Chemicals
Sigma Aldrich
Selleck Chemicals -
S1866
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Research Area: Immunology Biological Activity: Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects. Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. [1] |
PATENTS
PATENTS
PubChem Patent
Google Patent