2-aminoacetamide hydrochloride

• ChemBase ID: 49258
• Molecular Formular: C2H7ClN2O
• Molecular Mass: 110.54278
• Monoisotopic Mass: 110.02469053
• SMILES: C(=O)(N)CN.Cl
• Canonical SMILES: NCC(=O)N.Cl
• InChI: InChI=1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H
• InChIKey: WKNMKGVLOWGGOU-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 2-aminoacetamide hydrochloride
• IUPAC Traditional name: glycine amide hydrochloride; glycinamide hydrochloride
• Synonyms: GLYCINAMIDE HYDROCHLORIDE; 2-Aminoacetamide hydrochloride; H-Gly-NH2.HCl; 2-Aminoacetamide hydrochloride; GLYCINEAMIDE HCl; Glycinamide hydrochloride; 甘氨酰胺.盐酸盐; 甘氨酰胺 盐酸盐

Database IDs

• CAS Number: 1668-10-6
• EC Number: 216-789-1
• MDL Number: MFCD00013008
• Beilstein Number: 3554199
• PubChem SID: 162054021; 24895244; 24873333
• PubChem CID: 2723639

CALCULATED PROPERTIES

• Acid pKa: 16.374952
• H Acceptors: 2
• H Donor: 2
• LogD (pH = 5.5): -4.4525604
• LogD (pH = 7.4): -2.7703586
• Log P: -1.9544182
• Molar Refractivity: 17.8256 cm^3
• Polarizability: 7.1859527 Å^3
• Polar Surface Area: 69.11 Å^2
• Rotatable Bonds: 1
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: H2O: soluble0.1 g/mL, clear, colorless
• Melting Point: 199 - 201°C; 204 °C (dec.)(lit.); ca 204°C dec.
• Absorption Wavelength: λ: 260 nm Amax: 0.1
• Hydrophobicity(logP): -1.871
• pKa: 8.1 (25°C); 8.20 (20°C)

Safety Information

• Storage Condition: 0°C
• Storage Warning: Hygroscopic; IRRITANT
• German water hazard class: 3
• TSCA Listed: false; 否
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Product Information

• Purity: ≥99.0% (AT); 95%; 97%; 98%
• Cation Traces: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• λ: 0.5 M in H2O
• Linear Formula: NH2CH2CONH2 · HCl

DETAILS

MP Biomedicals - 02101822

Hydrochloride
Crystalline
pKa=8.1 at 25°C
Buffer useful in the physiological pH range.

MP Biomedicals - 05204258

MP Biomedicals Rare Chemical collection

Sigma Aldrich - G6104

Application
Buffer useful in the physiological pH range.
Packaging
25 g in poly bottle
5 g in glass bottle

Sigma Aldrich - 50070

Other Notes
Use in peptide coupling1.