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2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4,7-dien-17-ol
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ChemBase ID:
4455
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Molecular Formular:
C21H32N2O
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Molecular Mass:
328.49158
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Monoisotopic Mass:
328.25146365
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SMILES and InChIs
SMILES:
CC12Cc3c[nH]nc3CC1CCC1C2CCC2(C)C1CCC2(C)O
Canonical SMILES:
CC12Cc3c[nH]nc3CC1CCC1C2CCC2(C1CCC2(C)O)C
InChI:
InChI=1S/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)
InChIKey:
LKAJKIOFIWVMDJ-UHFFFAOYSA-N
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Cite this record
CBID:4455 http://www.chembase.cn/molecule-4455.html
NAMES AND DATABASE IDS
NAMES AND DATABASE IDS
Names Database IDs
IUPAC name
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2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4,7-dien-17-ol
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IUPAC Traditional name
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2,17,18-trimethyl-6,7-diazapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4,7-dien-17-ol
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Brand Name
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Winstrol
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Winstrol Depot (intramuscular injection)
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Stromba
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Synonyms
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CAS Number
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PubChem SID
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PubChem CID
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DATA SOURCES
DATA SOURCES
All Sources Commercial Sources Non-commercial Sources
Data Source
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Data ID
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Price
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CALCULATED PROPERTIES
CALCULATED PROPERTIES
JChem
ALOGPS 2.1
Acid pKa
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16.234053
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H Acceptors
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2
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H Donor
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2
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LogD (pH = 5.5)
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3.8062527
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LogD (pH = 7.4)
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3.8072276
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Log P
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3.80724
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Molar Refractivity
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96.7977 cm3
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Polarizability
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37.831547 Å3
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Polar Surface Area
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48.91 Å2
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Rotatable Bonds
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0
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Lipinski's Rule of Five
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true
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Log P
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4.33
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LOG S
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-5.28
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Solubility (Water)
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1.73e-03 g/l
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PROPERTIES
PROPERTIES
Bioassay(PubChem)
DETAILS
DETAILS
DrugBank
DrugBank -
DB06718
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Item |
Information |
Drug Groups
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approved |
Description
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Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes. |
Indication |
Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating C1-inhibitor deficient hereditary angioedema. C1-inhibitor is a protease that inhibits the complement system (part of the innate immune system), a biochemical chain of reactions which assists the body in removing pathogens from the body. Stanozolol may help control attacks of hereditary angioedema. Stanozolol can be administered orally or intramuscularly. |
Pharmacology |
Stanozolol is a synthetic anabolic-androgenic steroid (AAS), which promotes cell growth (anabolism) and development/maintenance of masculine characteristics (androgenism). |
Half Life |
24 hours |
References |
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Guilarte M, Luengo O, Nogueiras C, Labrador-Horrillo M, Munoz E, Lopez A, Cardona V: Acquired angioedema associated with hereditary angioedema due to C1 inhibitor deficiency. J Investig Allergol Clin Immunol. 2008;18(2):126-30.
[Pubmed]
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Thevis M, Schanzer W: Synthetic anabolic agents: steroids and nonsteroidal selective androgen receptor modulators. Handb Exp Pharmacol. 2010;(195):99-126.
[Pubmed]
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Sloane DE, Lee CW, Sheffer AL: Hereditary angioedema: Safety of long-term stanozolol therapy. J Allergy Clin Immunol. 2007 Sep;120(3):654-8.
[Pubmed]
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External Links |
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PATENTS
PATENTS
PubChem Patent
Google Patent