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76-19-7 molecular structure
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octafluoropropane

ChemBase ID: 438
Molecular Formular: C3F8
Molecular Mass: 188.0193256
Monoisotopic Mass: 187.98722576
SMILES and InChIs

SMILES:
FC(F)(C(F)(F)F)C(F)(F)F
Canonical SMILES:
FC(C(F)(F)F)(C(F)(F)F)F
InChI:
InChI=1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChIKey:
QYSGYZVSCZSLHT-UHFFFAOYSA-N

Cite this record

CBID:438 http://www.chembase.cn/molecule-438.html

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NAMES AND DATABASE IDS

NAMES AND DATABASE IDS

Names Database IDs
IUPAC name
octafluoropropane
IUPAC Traditional name
perflutren
definity
Brand Name
Definity
Freon 218
Genetron 218
Octafluoropropane
Perfluoropropane
Perfluoropropane 99+%
Perfluoropropaneminimum
Perflutren [USAN]
Propane, octafluoro-
Synonyms
Perflutren
Octafluoropropane
Perfluoropropane (PFC-218) 99.9%
Freon 218
Perfluoropropane
RC 218, PFC 218
R218
Flutec PP30
genetron 218
Octafluoropropane
CAS Number
76-19-7
MDL Number
MFCD00039239
PubChem SID
46506030
160963901
PubChem CID
6432
CHEBI ID
31980
CHEMBL
1663
Chemspider ID
6192
DrugBank ID
DB00556
KEGG ID
D01738
Unique Ingredient Identifier
CK0N3WH0SR
Wikipedia Title
Octafluoropropane

DATA SOURCES

DATA SOURCES

All Sources Commercial Sources Non-commercial Sources
Data Source Data ID Price
Apollo Scientific
PC6210 external link Add to cart Please log in.

CALCULATED PROPERTIES

CALCULATED PROPERTIES

JChem ALOGPS 2.1
H Acceptors H Donor
LogD (pH = 5.5) 2.78236  LogD (pH = 7.4) 2.78236 
Log P 2.78236  Molar Refractivity 17.5372 cm3
Polarizability 6.707999 Å3 Polar Surface Area 0.0 Å2
Rotatable Bonds Lipinski's Rule of Five true 
Log P 2.96  LOG S -3.11 
Solubility (Water) 1.46e-01 g/l 

PROPERTIES

PROPERTIES

Physical Property Safety Information Bioassay(PubChem)
Solubility
5.7 mg/L expand Show data source
Apperance
Colorless gas with
faintly sweet odor
expand Show data source
Melting Point
-183 °C (90.15 K) expand Show data source
-183°C expand Show data source
Boiling Point
-36.7 °C (236.45 K) expand Show data source
-39°C expand Show data source
Flash Point
N/A expand Show data source
none°C expand Show data source
Density
1.352 expand Show data source
8.17 g/l, gas expand Show data source
Hydrophobicity(logP)
3 expand Show data source
Storage Warning
Flammable expand Show data source
RTECS
TZ5255000 expand Show data source
Safety Statements
R R: ?
S: ?
expand Show data source
Main Hazard
Suffocation expand Show data source
NFPA704
NFPA 704 diagram
1
expand Show data source

DETAILS

DETAILS

DrugBank DrugBank Apollo Scientific Apollo Scientific Wikipedia Wikipedia
DrugBank - DB00556 external link
Item Information
Drug Groups approved
Description Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, is comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. When exposed to ultrasound waves, the microspheres resonate and "echo" strong signals back to the ultrasound machine. The difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Indication Use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.
Pharmacology Perflutren, a diagnostic drug that is intended to be used for contrast enhancement during the indicated echocardiographic procedures, comprised of lipid-coated microspheres filled with octafluoropropane(OFP) gas. It provide contrast enhancement of the endocardial borders during echocardiography. The perflutren lipid microspheres exhibit lower acoustic impedance than blood and enhance the intrinsic backscatter of blood.
Affected Organisms
Humans and other mammals
Biotransformation OFP is not metabolized. The phospholipid components of the microspheres are thought to be metabolized to free fatty acids.
Half Life The mean half-life of OFP in blood 1.9 minutes
External Links
RxList
Drugs.com
Apollo Scientific Ltd - PC6210 external link
Cylinder - 1/4" NPT connection

REFERENCES

REFERENCES

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PATENTS

PATENTS

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