N-(2-oxo-1,2,3,4-tetrahydroquinolin-4-yl)pyrazolo[1,5-a]pyridine-7-carboxamide

• ChemBase ID: 430120
• Molecular Formular: C17H14N4O2
• Molecular Mass: 306.31866
• Monoisotopic Mass: 306.11167571
• SMILES: c1(n2c(ccn2)ccc1)C(=O)NC1CC(=O)Nc2c1cccc2
• Canonical SMILES: O=C1CC(NC(=O)c2cccc3n2ncc3)c2c(N1)cccc2
• InChI: InChI=1S/C17H14N4O2/c22-16-10-14(12-5-1-2-6-13(12)19-16)20-17(23)15-7-3-4-11-8-9-18-21(11)15/h1-9,14H,10H2,(H,19,22)(H,20,23)
• InChIKey: YLFMHMRPKFITKE-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: N-(2-oxo-1,2,3,4-tetrahydroquinolin-4-yl)pyrazolo[1,5-a]pyridine-7-carboxamide
• IUPAC Traditional name: N-(2-oxo-3,4-dihydro-1H-quinolin-4-yl)pyrazolo[1,5-a]pyridine-7-carboxamide
• Synonyms: N-(2-oxo-1,2,3,4-tetrahydroquinolin-4-yl)pyrazolo[1,5-a]pyridine-7-carboxamide

CALCULATED PROPERTIES

JChem

• Acid pKa: 13.295681
• H Acceptors: 3
• H Donor: 2
• LogD (pH = 5.5): 1.4577379
• LogD (pH = 7.4): 1.4577916
• Log P: 1.4577928
• Molar Refractivity: 97.1166 cm^3
• Polarizability: 32.372612 Å^3
• Polar Surface Area: 75.5 Å^2
• Rotatable Bonds: 2
• Lipinski's Rule of Five: true

供应商提供(Chembridge)

• H Acceptors: 3
• H Donor: 2
• Log P: 1.02
• LOG S: -2.31
• Polar Surface Area: 75.5 Å^2
• Rotatable Bonds: 2