6-(2H5)phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride

• ChemBase ID: 178486
• Molecular Formular: C11H13ClN2S
• Molecular Mass: 240.75232
• Monoisotopic Mass: 240.04879711
• SMILES: Cl.S1CCN2C1=NC(C2)c1ccccc1
• Canonical SMILES: C1CN2C(=NC(C2)c2ccccc2)S1.Cl
• InChI: InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
• InChIKey: LAZPBGZRMVRFKY-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 6-(^2H₅)phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
• IUPAC Traditional name: 6-(^2H₅)phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
• Synonyms: 2,3,5,6-Tetrahydro-6-phenyl-imidazo[2,1-b]thiazole-d5 Hydrochloride; (+/-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole-d5 Hydrochloride; (+/-)-Tetramisole-d5 Hydrochloride; Anthelvet-d5; Citarin-d5; Concurat-d5; Curaminth-d5; DL-Tetramisole-d5 Hydrochloride; Verminject-d5; NSC 170985-d5; NSC 215179-d5; Tetramisole-d5 Hydrochloride

Database IDs

• CAS Number: 1193021-85-6
• PubChem SID: 164234396
• PubChem CID: 71312483

CALCULATED PROPERTIES

• H Acceptors: 2
• H Donor: 0
• LogD (pH = 5.5): 0.91581506
• LogD (pH = 7.4): 2.220205
• Log P: 2.358227
• Molar Refractivity: 60.0784 cm^3
• Polarizability: 23.0503 Å^3
• Polar Surface Area: 15.6 Å^2
• Rotatable Bonds: 1
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Methanol
• Apperance: White Solid
• Melting Point: 224-226°C

DETAILS

Toronto Research Chemicals - T305682

Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.

REFERENCES

• Janjatovic, A., et al.: J. Vet. Pharmacol. Ther., 31, 328 (2008)
• Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2008)