6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride

• ChemBase ID: 178485
• Molecular Formular: C11H13ClN2S
• Molecular Mass: 240.75232
• Monoisotopic Mass: 240.04879711
• SMILES: Cl.S1CCN2C1=NC(C2)c1ccccc1
• Canonical SMILES: C1CN2C(=NC(C2)c2ccccc2)S1.Cl
• InChI: InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
• InChIKey: LAZPBGZRMVRFKY-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole hydrochloride
• IUPAC Traditional name: tetramisole hydrochloride hydrochloride
• Synonyms: 2,3,5,6-Tetrahydro-6-phenyl-imidazo[2,1-b]thiazole Hydrochloride; (+/-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole Hydrochloride; (+/-)-Tetramisole Hydrochloride; Anthelvet; Citarin; Concurat; Curaminth; DL-Tetramisole Hydrochloride; Verminject; NSC 170985; NSC 215179; Tetramisole Hydrochloride

Database IDs

• CAS Number: 5086-74-8
• PubChem SID: 164234395
• PubChem CID: 68628

CALCULATED PROPERTIES

• H Acceptors: 2
• H Donor: 0
• LogD (pH = 5.5): 0.91581506
• LogD (pH = 7.4): 2.220205
• Log P: 2.358227
• Molar Refractivity: 60.0784 cm^3
• Polarizability: 23.02744 Å^3
• Polar Surface Area: 15.6 Å^2
• Rotatable Bonds: 1
• Lipinski's Rule of Five: true

DETAILS

Toronto Research Chemicals - T305680

Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.

REFERENCES

• Janjatovic, A., et al.: J. Vet. Pharmacol. Ther., 31, 328 (2008)
• Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2008)