diiodo(methyl)arsane

• ChemBase ID: 173596
• Molecular Formular: CH3AsI2
• Molecular Mass: 343.76506
• Monoisotopic Mass: 343.7540171
• SMILES: I[As](I)C
• Canonical SMILES: C[As](I)I
• InChI: InChI=1S/CH3AsI2/c1-2(3)4/h1H3
• InChIKey: ZKGSUVMABCXPKK-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: diiodo(methyl)arsane
• IUPAC Traditional name: diiodo(methyl)arsane
• Synonyms: Diiodomethylarsine; Methylarsine Diiodide; Methylarsonous diiodide; Methyldiiodoarsine

Database IDs

• CAS Number: 7207-97-8
• PubChem SID: 164229506
• PubChem CID: 23612

CALCULATED PROPERTIES

• H Acceptors: 0
• H Donor: 0
• LogD (pH = 5.5): 1.9439
• LogD (pH = 7.4): 1.9439
• Log P: 1.9439
• Molar Refractivity: 32.6273 cm^3
• Polarizability: 17.61539 Å^3
• Polar Surface Area: 0.0 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Chloroform
• Apperance: Yellow Solid

Safety Information

• Storage Condition: -20°C Freezer

DETAILS

Toronto Research Chemicals - M303685

Methyldiiodoarsine is an arsenite metabolite in wild type CHO cells and in cells deficient in excision repair cross-complementing 1 and 2. Methyldiiodoarsine is an inhibitor of Thioredoxin reductase, an enzyme involved in the response of the cell to oxida

REFERENCES

• Lin, S. et al.: Chem. Res. Toxicol., 12, 924 (1999)
• Vahidnia, A. et al.: Toxicol. Vitro, 22, 1662 (1999)
• Patrick, J. et al. Chem. Res. Toxicol., 14, 651 (1999)