(1S,2R,8R,10R,11S,14S,15S)-8,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one

• ChemBase ID: 171348
• Molecular Formular: C19H28O3
• Molecular Mass: 304.42382
• Monoisotopic Mass: 304.20384476
• SMILES: C1CC(=O)C=C2[C@]1([C@@H]1[C@@H](C[C@H]2O)[C@H]2[C@](CC1)([C@H](CC2)O)C)C
• Canonical SMILES: O=C1CC[C@]2(C(=C1)[C@H](O)C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C)C
• InChI: InChI=1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1
• InChIKey: XSEGWEUVSZRCBC-ZVBLRVHNSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (1S,2R,8R,10R,11S,14S,15S)-8,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: 6β-hydroxytestosterone
• Synonyms: (6β,17β)-6,17-Dihydroxyandrost-4-en-3-one; 4-Androstene-6β,17β-diol-3-one; 6β,17β-Dihydroxy-4-androstene-3-one; 6β,17β-Dihydroxyandrost-4-en-3-one; NSC 9721; 6β-Hydroxy Testosterone

Database IDs

• CAS Number: 62-99-7
• PubChem SID: 164227258
• PubChem CID: 65543

CALCULATED PROPERTIES

• Acid pKa: 14.545773
• H Acceptors: 3
• H Donor: 2
• LogD (pH = 5.5): 2.134612
• LogD (pH = 7.4): 2.134612
• Log P: 2.1346123
• Molar Refractivity: 85.9453 cm^3
• Polarizability: 33.878315 Å^3
• Polar Surface Area: 57.53 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Chloroform; Methanol
• Apperance: White Solid
• Melting Point: 210-212°C

Safety Information

• Storage Condition: Controlled Substance, -20°C Freezer

DETAILS

Toronto Research Chemicals - H956750

A metabolite of Testosterone (T155000).CONTROLLED SUBSTANCE

REFERENCES

• Brandon, E., et al.: Toxicol. Appl. Pharmacol., 189, 233 (2003)
• Froehlich, A., et al.: Drug Metab. Dispos., 33, 1532 (2003)
• Schmelzer, E., et al.: Xenobiotica, 6, 693 (2003)
• Jasmund, I., et al.: Biomol. Eng., 24, 59 (2003)