(2R,3R,4R)-5-(acetyloxy)-4-(benzoyloxy)-2-[(benzoyloxy)methyl]oxolan-3-yl benzoate

• ChemBase ID: 159507
• Molecular Formular: C28H24O9
• Molecular Mass: 504.48476
• Monoisotopic Mass: 504.14203235
• SMILES: [C@H]1([C@@H](COC(=O)c2ccccc2)OC([C@@H]1OC(=O)c1ccccc1)OC(=O)C)OC(=O)c1ccccc1
• Canonical SMILES: CC(=O)OC1O[C@@H]([C@H]([C@H]1OC(=O)c1ccccc1)OC(=O)c1ccccc1)COC(=O)c1ccccc1
• InChI: InChI=1S/C28H24O9/c1-18(29)34-28-24(37-27(32)21-15-9-4-10-16-21)23(36-26(31)20-13-7-3-8-14-20)22(35-28)17-33-25(30)19-11-5-2-6-12-19/h2-16,22-24,28H,17H2,1H3/t22-,23-,24-,28?/m1/s1
• InChIKey: GCZABPLTDYVJMP-ASAMFVBJSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (2R,3R,4R)-5-(acetyloxy)-4-(benzoyloxy)-2-[(benzoyloxy)methyl]oxolan-3-yl benzoate
• IUPAC Traditional name: (2R,3R,4R)-5-(acetyloxy)-4-(benzoyloxy)-2-[(benzoyloxy)methyl]oxolan-3-yl benzoate
• Synonyms: 1-O-Acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose; D-Ribofuranose 1-Acetate 2,3,5-Tribenzoate; 1-O-Acetyl-2,3,5-tri-O-benzoyl-D-ribose; 1-O-Acetyl-2,3,5-tri-O-benzoylribose; 1-O-Acetyl-2,3,5-tri-O-benzoyl-α,β-D-ribofuranose

Database IDs

• CAS Number: 14215-97-5; 6974-32-9
• MDL Number: MFCD00005357
• PubChem SID: 162253642
• PubChem CID: 10929242

CALCULATED PROPERTIES

• H Acceptors: 5
• H Donor: 0
• LogD (pH = 5.5): 5.6248207
• LogD (pH = 7.4): 5.6248207
• Log P: 5.6248207
• Molar Refractivity: 128.5784 cm^3
• Polarizability: 50.93317 Å^3
• Polar Surface Area: 114.43 Å^2
• Rotatable Bonds: 12
• Lipinski's Rule of Five: false

PROPERTIES

Product Information

• Purity: 98%

DETAILS

Toronto Research Chemicals - A189325

An inhibitor of neutrophil-keyhole limpet hemocyanin adhesion. Anti-inflammatory agent.

REFERENCES

• Shappell, S., et al.: J. Immunol., 144, 2702 (1990)
• Ross, L., et al.: J. Biol. Chem., 267, 8537 (1990)
• Granger, D., et al.: J. Leukoc. Biol., 55, 662 (1990)