• ChemBase ID: 152835
• Molecular Formular: C14H17N2
• Molecular Mass: 213.29818
• Monoisotopic Mass: 213.13917355
• SMILES: *c1ccc(cc1)CN=C=NC1CCCCC1
• Canonical SMILES: *c1ccc(cc1)CN=C=NC1CCCCC1
• InChI: InChI=

NAMES AND DATABASE IDS

Names

• Synonyms: N,N′-Dicyclohexylcarbodiimide, polymer-bound; N-Benzyl-N′-cyclohexylcarbodiimide, polymer-bound; N-Cyclohexylcarbodiimide, 0.8-1.0 mmol/g on Merrifield resin; 聚合物键合型 N,N′-二环己基碳二亚胺; 聚合物键合型 N-苄基-N′-环己基碳二亚胺; N-环己基碳二酰亚胺, 0.8-1.0 mmol/g 于Merrifield 树脂

Database IDs

• EC Number: 215-325-5; 000-000-0
• MDL Number: MFCD03410276; MFCD01867681
• PubChem SID: 162246978; 24879975; 24844955
• PubChem CID: 5067457

PROPERTIES

Physical Property

• Flash Point: 156.2 °F; 69 °C

Safety Information

• Storage Warning: Moisture Sensitive
• European Hazard Symbols: Harmful (Xn)
• German water hazard class: 2; 3
• Risk Statements: 21-41-43; 22-36/37/38
• Safety Statements: 24-26-37/39; 26
• TSCA Listed: 否
• GHS Pictograms: GHS05; GHS07
• GHS Signal Word: Danger; Warning
• GHS Hazard statements: H302-H315-H317-H319-H335; H312-H317-H318
• GHS Precautionary statements: P261-P280-P305 + P351 + P338; P280-P305 + P351 + P338
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Product Information

• Particle Size: 100-200 mesh; 100-300 mesh
• Extent of Labeling: ~1.3 mmol/g N loading; 1.0-2.0 mmol/g loading
• Matrix: cross-linked with 2% DVB
• Crosslinking: 1 % cross-linked with divinylbenzene

DETAILS

Sigma Aldrich - 561843

Application
Polymer-supported coupling reagent. Used in the preparation of a dicarboxamidocyclopentanol library.
Packaging
5, 25, 100 g in glass bottle

Sigma Aldrich - 00787

Other Notes
Immobilized carbodiimide for peptide coupling allowing simple removal of excess reagent and the urea by-product.1

REFERENCES

• Has been used as a mediator in the synthesis of amides from amines and carboxylic acids where the excess acid and urea by-product remain attached to the resin: Org. Synth. Coll.,6, 951 (1988).