bis[dimethyl(phenyl)silyl]amine

• ChemBase ID: 150578
• Molecular Formular: C16H23NSi2
• Molecular Mass: 285.53152
• Monoisotopic Mass: 285.13690281
• SMILES: C[Si](C)(c1ccccc1)N[Si](C)(C)c1ccccc1
• Canonical SMILES: C[Si](c1ccccc1)(N[Si](c1ccccc1)(C)C)C
• InChI: InChI=1S/C16H23NSi2/c1-18(2,15-11-7-5-8-12-15)17-19(3,4)16-13-9-6-10-14-16/h5-14,17H,1-4H3
• InChIKey: HIMXYMYMHUAZLW-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: bis[dimethyl(phenyl)silyl]amine
• IUPAC Traditional name: bis[dimethyl(phenyl)silyl]amine
• Synonyms: DPTMDS; 1,3-Diphenyl-1,1,3,3-tetramethyldisilazane; 1,1,3,3-Tetramethyl-1,3-diphenyldisilazane; 1,3-联苯基四甲基二硅氮烷; 1,1,3,3-四甲基-1,3-二苯基二硅胺烷

Database IDs

• CAS Number: 3449-26-1
• EC Number: 222-372-5
• MDL Number: MFCD00042916
• Beilstein Number: 2738118
• PubChem SID: 162244739; 24862485; 24867141
• PubChem CID: 76988

CALCULATED PROPERTIES

• H Acceptors: 1
• H Donor: 1
• LogD (pH = 5.5): -0.2537273
• LogD (pH = 7.4): -0.25006366
• Log P: 3.3533
• Molar Refractivity: 87.9839 cm^3
• Polarizability: 34.742714 Å^3
• Polar Surface Area: 12.03 Å^2
• Rotatable Bonds: 4
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Boiling Point: 96-100 °C/0.1 mmHg(lit.)
• Flash Point: 113 °C; 235.4 °F
• Density: 0.985 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.538; n20/D 1.538(lit.)

Safety Information

• European Hazard Symbols: Irritant (Xi)
• German water hazard class: 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• GHS Precautionary statements: P261-P305 + P351 + P338
• Personal Protective Equipment: Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Product Information

• Purity: ≥97.0% (GC); 96%
• Grade: for GC derivatization
• Linear Formula: [C6H5Si(CH3)2]2NH

DETAILS

Sigma Aldrich - 365157

Packaging
1, 10 g in glass bottle

Sigma Aldrich - 43340

Other Notes
For the deactivation of glass capillary columns by persilylation 1,2; The lithium amide is used for the selective formation of (Z)-enolates from ketones 3