(methoxymethyl)trimethylsilane

• ChemBase ID: 145715
• Molecular Formular: C5H14OSi
• Molecular Mass: 118.24956
• Monoisotopic Mass: 118.0813916
• SMILES: COC[Si](C)(C)C
• Canonical SMILES: COC[Si](C)(C)C
• InChI: InChI=1S/C5H14OSi/c1-6-5-7(2,3)4/h5H2,1-4H3
• InChIKey: PPNQXAYCPNTVHH-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (methoxymethyl)trimethylsilane
• IUPAC Traditional name: (methoxymethyl)trimethylsilane
• Synonyms: (Trimethylsilyl)methyl methyl ether; (Methoxymethyl)trimethylsilane; (三甲基硅烷基)甲基甲醚; (甲氧基甲基)三甲基硅烷

Database IDs

• CAS Number: 14704-14-4
• MDL Number: MFCD00009843
• Beilstein Number: 1732033
• PubChem SID: 24856781; 162239918
• PubChem CID: 139809

CALCULATED PROPERTIES

• H Acceptors: 1
• H Donor: 0
• LogD (pH = 5.5): 2.1886
• LogD (pH = 7.4): 2.1886
• Log P: 2.1886
• Molar Refractivity: 28.3838 cm^3
• Polarizability: 13.562283 Å^3
• Polar Surface Area: 9.23 Å^2
• Rotatable Bonds: 2
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Boiling Point: 83 °C/740 mmHg(lit.)
• Flash Point: 21.2 °F; -6 °C
• Density: 0.758 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.39(lit.); n20/D 1.391

Safety Information

• European Hazard Symbols: Flammable (F); Irritant (Xi)
• UN Number: 3271
• German water hazard class: 3
• Hazard Class: 3
• Packing Group: 2
• Risk Statements: 11-36/37/38
• Safety Statements: 16-26-28-29-33-36/37/39
• GHS Pictograms: GHS02; GHS07
• GHS Signal Word: Danger
• GHS Hazard statements: H225-H315-H319-H335
• GHS Precautionary statements: P210-P261-P305 + P351 + P338
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• RID/ADR: UN 3271 3/PG 2

Product Information

• Purity: ≥95% (GC); 98%
• Grade: technical
• Linear Formula: CH3OCH2Si(CH3)3

DETAILS

Sigma Aldrich - 277711

Packaging
10 g in glass bottle

Sigma Aldrich - 65097

Other Notes
The lithiated reagent reacts with carbonyls to give aldehydes or their enol ethers1,2; Other (trimethylsilyl)methyl compounds can readily be prepared from (methoxymethyl)trimethylsilane3