(chloromethoxy)tris(propan-2-yl)silane

• ChemBase ID: 139386
• Molecular Formular: C10H23ClOSi
• Molecular Mass: 222.82752
• Monoisotopic Mass: 222.12066957
• SMILES: CC(C)[Si](C(C)C)(C(C)C)OCCl
• Canonical SMILES: ClCO[Si](C(C)C)(C(C)C)C(C)C
• InChI: InChI=1S/C10H23ClOSi/c1-8(2)13(9(3)4,10(5)6)12-7-11/h8-10H,7H2,1-6H3
• InChIKey: SYZFQLUYDBIQCR-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (chloromethoxy)tris(propan-2-yl)silane
• IUPAC Traditional name: (chloromethoxy)triisopropylsilane
• Synonyms: TOMCl; (Chloromethoxy)triisopropylsilane; (Triisopropylsiloxy)methyl chloride; (氯甲氧基)三异丙基硅烷; 异丙氧基硅氯甲烷

Database IDs

• CAS Number: 217300-17-9
• MDL Number: MFCD05865265
• PubChem SID: 24889480; 162233634
• PubChem CID: 16218752

CALCULATED PROPERTIES

• H Acceptors: 1
• H Donor: 0
• LogD (pH = 5.5): 4.2952
• LogD (pH = 7.4): 4.2952
• Log P: 4.2952
• Molar Refractivity: 56.362 cm^3
• Polarizability: 24.598036 Å^3
• Polar Surface Area: 9.23 Å^2
• Rotatable Bonds: 5
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Density: 0.96 g/mL at 20 °C(lit.)

Safety Information

• German water hazard class: 3
• Personal Protective Equipment: Eyeshields, Gloves

Product Information

• Purity: ≥95.0% (GC)
• Empirical Formula (Hill Notation): C10H23ClOSi

DETAILS

Sigma Aldrich - 91415

Other Notes
Fluoride-labile 2′-O-protecting group for RNA oligonucleotide synthesis1,2
Packaging
1, 5 mL in glass bottle