(5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol

• ChemBase ID: 134419
• Molecular Formular: C12H22O11
• Molecular Mass: 342.29648
• Monoisotopic Mass: 342.11621152
• SMILES: C(C1[C@H](C(C(C(O1)O)O)O)O[C@H]1C(C(C(C(O1)CO)O)O)O)O
• Canonical SMILES: OCC1OC(O)C(C([C@@H]1O[C@@H]1OC(CO)C(C(C1O)O)O)O)O
• InChI: InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1
• InChIKey: GUBGYTABKSRVRQ-WFVLMXAXSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol
• IUPAC Traditional name: (5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol
• Synonyms: DEAE-Sephacel®; Diethylaminoethyl–Sephacel®; DEAE-Cellulose; Express-Ion™ exchanger? D free base; Cellulose, microcrystalline; Cellulose DEAE; Diethylaminoethyl-cellulose; DEAE-Cellulose; 纤维素, 微晶

Database IDs

• CAS Number: 9004-34-6; 9013-34-7
• EC Number: 232-674-9
• MDL Number: MFCD00146622; MFCD00081512
• Merck Index: 141965
• PubChem SID: 24894027; 24858386; 24896090; 24893780; 24894457; 24893308; 162228695
• PubChem CID: 16211032

CALCULATED PROPERTIES

• Acid pKa: 11.2543745
• H Acceptors: 11
• H Donor: 8
• LogD (pH = 5.5): -4.703376
• LogD (pH = 7.4): -4.7034354
• Log P: -4.703375
• Molar Refractivity: 68.3367 cm^3
• Polarizability: 28.969793 Å^3
• Polar Surface Area: 189.53 Å^2
• Rotatable Bonds: 4
• Lipinski's Rule of Five: false

PROPERTIES

Physical Property

• Apperance: aqueous ethanol suspension; fibers; preswollen, microgranular
• Flash Point: 129.2 °F; 54 °C

Safety Information

• European Hazard Symbols: Irritant (Xi)
• UN Number: 1170
• German water hazard class: 1; 3
• Hazard Class: 3
• Packing Group: 3
• Risk Statements: 10; 37
• TSCA Listed: 是
• GHS Pictograms: GHS02; GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H226; H335
• GHS Precautionary statements: P261-P304+P340-P312-P405-P403+P233-P501A
• RID/ADR: UN 1170 3/PG 3
• Storage Temperature: 2-8°C

Product Information

• Particle Size: 100-200 μm; 40-160 μm (wet); 60-130 μm
• Pore Size: ~1,000,000 Da exclusion limit
• Impurities: ~70% water
• Contains: ~70% moisture content
• Binding Capacity: 100-140 μeq/mL, gel
• pH Range: 2 - 9
• Matrix Active Group: DEAE (diethylaminoethyl)
• Feature: flow rate 150 cm/hr
• Capacity: ~0.3 meq/g capacity; ~0.3 meq/g(as supplied); ~1.0 meq/g small ion capacity; ~1.0 meq/g(dry); 1 meq/g

DETAILS

Sigma Aldrich - D3764

Application
DEAE-Cellulose is used in ion exchange chromatography, protein chromatography and anion exchange media. DEAE cellulose has been used to study acute myocardial infarction

Sigma Aldrich - E2145

Application
Express-Ion exchangers are weakly basic anion exchangers used in protein chromatography, ion exchange chromatography, cation exchange media, cellulose ion exchange TLC adsorbents and DEAE-cellulose anion exchange TLC adsorbents.
Legal Information
Express-Ion is a trademark of Whatman International Ltd.

Sigma Aldrich - D6418

Application
DEAE-Cellulose is used in ion exchange chromatography, protein chromatography and anion exchange media. DEAE cellulose has been used to study acute myocardial infarction.

Sigma Aldrich - I6505

包装
1 L in glass bottle
100, 500 mL in glass bottle
Physical form
Suspension in 20% ethanol
Application
Diethylaminoethyl Sephacel is used in protein chromatography, ion exchange chromatography and anion exchange media. Diethylaminoethyl Sephacel has been used to study sperm motility, sperm capacitation and sperm-oocyte interactions. Diethylaminoethyl Sephacel has also been used to study patients with IgA nephropathy.
法律信息
Sephacel is a registered trademark of GE Healthcare