2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-9H-purin-7-ium-6-olate

• ChemBase ID: 133755
• Molecular Formular: C11H15N5O5
• Molecular Mass: 297.2673
• Monoisotopic Mass: 297.10731861
• SMILES: C[n+]1cn(c2c1c(nc(n2)N)[O-])[C@H]1[C@@H]([C@@H]([C@H](O1)CO)O)O
• Canonical SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1c[n+](c2c1nc(N)nc2[O-])C
• InChI: InChI=1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/t4-,6-,7-,10-/m1/s1
• InChIKey: OGHAROSJZRTIOK-KQYNXXCUSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-9H-purin-7-ium-6-olate
• IUPAC Traditional name: 7-methylguanosine
• Synonyms: 7-Methylguanosine

Database IDs

• CAS Number: 20244-86-4
• MDL Number: MFCD16661197
• Beilstein Number: 3713683
• PubChem SID: 162228032; 24896562
• PubChem CID: 6474236

CALCULATED PROPERTIES

• Acid pKa: 9.770023
• H Acceptors: 8
• H Donor: 4
• LogD (pH = 5.5): -5.620555
• LogD (pH = 7.4): -5.6223283
• Log P: -5.6205206
• Molar Refractivity: 80.8655 cm^3
• Polarizability: 26.956036 Å^3
• Polar Surface Area: 153.59 Å^2
• Rotatable Bonds: 2
• Lipinski's Rule of Five: true

PROPERTIES

Safety Information

• German water hazard class: 3
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C

Product Information

• Purity: ≥90%; ≥99.0% (HPLC)
• Impurities: ≤13% water
• Empirical Formula (Hill Notation): C11H15N5O5

DETAILS

Sigma Aldrich - M0627

Application
7-Methylguanosine may be used to characterize and study the metabolism of naturally occurring methylated guanosines in RNAs.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M0627.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.