6,7-dimethoxy-2-phenylquinoxaline

• ChemBase ID: 132514
• Molecular Formular: C16H14N2O2
• Molecular Mass: 266.29456
• Monoisotopic Mass: 266.1055277
• SMILES: COc1cc2c(cc1OC)nc(cn2)c1ccccc1
• Canonical SMILES: COc1cc2nc(cnc2cc1OC)c1ccccc1
• InChI: InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3
• InChIKey: QNOXYUNHIGOWNY-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 6,7-dimethoxy-2-phenylquinoxaline
• IUPAC Traditional name: 6,7-dimethoxy-2-phenylquinoxaline
• Synonyms: 6,7-Dimethoxy-2-phenylquinoxaline; Tyrphostin AG 1296; Tyrphostin AG 1296 (AG 1296)

Database IDs

• CAS Number: 146535-11-7
• MDL Number: MFCD00270913
• PubChem SID: 162226791
• PubChem CID: 2049

CALCULATED PROPERTIES

• H Acceptors: 4
• H Donor: 0
• LogD (pH = 5.5): 3.0166352
• LogD (pH = 7.4): 3.0168092
• Log P: 3.0168116
• Molar Refractivity: 75.141 cm^3
• Polarizability: 32.113907 Å^3
• Polar Surface Area: 44.24 Å^2
• Rotatable Bonds: 3
• Lipinski's Rule of Five: true

PROPERTIES

Safety Information

• German water hazard class: 3
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C

Pharmacology Properties

• Target: PDGFR

Product Information

• Purity: ≥98%
• Salt Data: Free Base

DETAILS

Sigma Aldrich - T4057

Biochem/physiol Actions
Selective inhibitor of platelet-derived growth factor (PDGF) receptor protein.