NAMES AND DATABASE IDS
NAMES AND DATABASE IDS
Names Database IDs
IUPAC name
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(5R)-8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol hydrochloride
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IUPAC Traditional name
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(5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol hydrochloride
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Synonyms
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R(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
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R(+)-SCH-23390 hydrochloride
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(5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol Hydrochloride
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(R)-Sch 23390 Hydrochloride
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(R)-(+)-Sch 23390 Hydrochloride
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CAS Number
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MDL Number
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PubChem SID
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PubChem CID
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DATA SOURCES
DATA SOURCES
All Sources Commercial Sources Non-commercial Sources
CALCULATED PROPERTIES
CALCULATED PROPERTIES
JChem
Acid pKa
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7.7272134
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H Acceptors
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2
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H Donor
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1
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LogD (pH = 5.5)
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1.1550401
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LogD (pH = 7.4)
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2.7690248
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Log P
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3.0575705
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Molar Refractivity
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84.0176 cm3
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Polarizability
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32.255955 Å3
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Polar Surface Area
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23.47 Å2
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Rotatable Bonds
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1
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Lipinski's Rule of Five
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true
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DETAILS
DETAILS
Sigma Aldrich
TRC
Sigma Aldrich -
D054
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Frequently Asked Questions Live Chat and Frequently Asked Questions are available for this Product. Biochem/physiol Actions R(+)-SCH-23390 hydrochloride is a selective D1 dopamine receptor antagonist. Legal Information Sold with the permission of Schering-Plough. |
Sigma Aldrich -
C0206
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Biochem/physiol Actions Selective D1 dopamine receptor antagonist |
REFERENCES
REFERENCES
From Suppliers
Google Scholar
PubMed
Google Books
- • Hiroi, N., et al.: Brain Res., 552, 141 (1991)
- • Kafka, S., et al.: Eur. J .Pharmacol., 295, 147 (1991)
- • Meririnne, E., et al.: J. Pharmacol. Exp. Ther., 298, 539 (1991)
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PATENTS
PATENTS
PubChem Patent
Google Patent