sodium 2-oxopropanoate

• ChemBase ID: 129553
• Molecular Formular: C3H3NaO3
• Molecular Mass: 110.04389
• Monoisotopic Mass: 109.99798824
• SMILES: [Na+].[O-]C(=O)C(=O)C
• Canonical SMILES: CC(=O)C(=O)[O-].[Na+]
• InChI: InChI=1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
• InChIKey: DAEPDZWVDSPTHF-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: sodium 2-oxopropanoate
• IUPAC Traditional name: sodium 2-oxopropionate; sodium pyruvate
• Synonyms: α-ketopropionic acid sodium salt2-oxopropanoic acid sodium saltPyruvic acid sodium salt; Sodium pyruvate; Sodium Pyruvate; Sodium α-Ketopropionate; Pyruvic Acid Sodium Salt; Sodium pyruvate; α-Ketopropionic acid sodium salt; 2-Oxopropanoic acid sodium salt; Pyruvic acid sodium salt; Sodium pyruvate solution; α-酮基丙酸 钠盐; 2-氧代丙酸 钠盐; 乙酰甲酸 钠盐; 丙酮酸钠; 丙酮酸钠 溶液

Database IDs

• CAS Number: 113-24-6
• EC Number: 204-024-4
• MDL Number: MFCD00002586
• Beilstein Number: 3568341
• PubChem SID: 24899804; 24898303; 24898951; 162223844; 24898440; 24898552; 24898615
• PubChem CID: 23662274
• CHEBI ID: 50144
• CHEMBL: 181886
• Chemspider ID: 7931
• Unique Ingredient Identifier: POD38AIF08
• Wikipedia Title: Sodium_pyruvate

CALCULATED PROPERTIES

• Acid pKa: 2.9301233
• H Acceptors: 3
• H Donor: 0
• LogD (pH = 5.5): -2.4600048
• LogD (pH = 7.4): -3.4164543
• Log P: 0.06587395
• Molar Refractivity: 28.8268 cm^3
• Polarizability: 6.905475 Å^3
• Polar Surface Area: 57.2 Å^2
• Rotatable Bonds: 1
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: 100 mg/mL; H2O: soluble1 M, clear, colorless; H2O: soluble100 mg/mL
• Apperance: powder; solution
• Melting Point: >300 °C(lit.); >300°C

Safety Information

• German water hazard class: 2; 3
• TSCA Listed: 是
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C

Product Information

• Purity: ≥95.0%; ≥99%; ≥99.0% (NT); 99%
• Concentration: 100 mM
• Grade: Hybri-Max™; purum; ReagentPlus®; SAJ special grade
• Suitability: suitable for cell culture; suitable for hybridoma; suitable for insect cell culture; suitable for mouse embryo
• Impurities: ≤0.005% Phosphorus (P); ≤0.1% Insoluble matter; endotoxin, tested
• Cation Traces: Al: ≤0.0005%; Ca: ≤0.001%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH4+: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• Antion Traces: chloride (Cl-): ≤0.05%; sulfate (SO42-): ≤0.05%
• Sterility: sterile-filtered
• Quality Level: GMP; PREMIUM
• Product Line: BioReagent
• Linear Formula: CH3COCOONa

DETAILS

Sigma Aldrich - P5280

Biochem/physiol Actions
Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Sigma Aldrich - S8636

Application
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.

Sigma Aldrich - P4562

Application
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Sigma Aldrich - P3662

Application
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.
法律信息
Hybri-Max 商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 15990

Other Notes
Improves coliform recovery when present in culture medium1.

Sigma Aldrich - P2256

包装
10 mg in autosmp vl
5, 25, 100, 500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Toronto Research Chemicals - P998900

Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, wh

REFERENCES

• Wenzel, A., et al.: J. Neurosci., 21, 53 (2001)
• Martinez., et al.: Development, 6, 851 (2001)
• Nakayama, K., et al.: J. Biochem., 146, 757 (2001)
• Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2001)