sodium 2-(N-methyldodecanamido)acetate

• ChemBase ID: 129533
• Molecular Formular: C15H28NNaO3
• Molecular Mass: 293.37749
• Monoisotopic Mass: 293.19668804
• SMILES: CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+]
• Canonical SMILES: CCCCCCCCCCCC(=O)N(CC(=O)[O-])C.[Na+]
• InChI: InChI=1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
• InChIKey: KSAVQLQVUXSOCR-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: sodium 2-(N-methyldodecanamido)acetate
• IUPAC Traditional name: sodium 2-(N-methyldodecanamido)acetate
• Synonyms: Sodium lauroyl sarcosinate; Sarcosyl; Sodium N-dodecanoyl-N-methylglycinate; Sodium N-lauroylsarcosinate solution; N-Lauroylsarcosine sodium salt solution; N-Dodecanoyl-N-methylglycine sodium salt; Sarkosyl NL; N-Lauroylsarcosine sodium salt; 十二烷基肌氨酸钠 溶液; N-月桂酰肌氨酸 钠盐 溶液; N-十二烷酰基-N-甲基甘氨酸 钠盐; 肌氨酰 NL; N-月桂酰肌氨酸 钠盐; More...

Database IDs

• CAS Number: 137-16-6
• EC Number: 205-281-5
• MDL Number: MFCD00042728
• Beilstein Number: 5322974
• PubChem SID: 24874844; 24896478; 24874845; 24896393; 24896517; 162223825; 24874843; 24896419; More...
• PubChem CID: 23668817
• Wikipedia Title: Sodium_lauroyl_sarcosinate

CALCULATED PROPERTIES

• Acid pKa: 4.1243777
• H Acceptors: 3
• H Donor: 0
• LogD (pH = 5.5): 2.2061958
• LogD (pH = 7.4): 0.5132401
• Log P: 3.596701
• Molar Refractivity: 87.2169 cm^3
• Polarizability: 29.969442 Å^3
• Polar Surface Area: 60.44 Å^2
• Rotatable Bonds: 12
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: H2O: soluble0.1 M, clear, colorless to very faintly yellow; H2O: soluble1 M at 20 °C, clear, colorless
• Melting Point: -1°C
• Boiling Point: 100°C
• Flash Point: 267 °C; 512.6 °F
• Density: 1.033 g/mL at 20 °C
• Absorption Wavelength: λ: 260 nm Amax: 0.2; λ: 280 nm Amax: 0.06
• Critical Micelle Concentration: 14.6; 14.6 mM(20-25°C)
• Aggregation Number of Micelle: 2
• pH: 7.0-9.0 (25 °C); 7.0-9.0 (25 °C, 1 M in H2O)

Safety Information

• European Hazard Symbols: Toxic (T)
• German water hazard class: 1
• Risk Statements: 23-38-41
• Safety Statements: 22-26-37/39-38-45
• GHS Pictograms: GHS05; GHS06
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H318; H315-H318-H330
• GHS Precautionary statements: P260-P280-P284-P305 + P351 + P338-P310; P280-P305 + P351 + P338
• Personal Protective Equipment: Eyeshields, Gloves; Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Product Information

• Purity: ≥94%; ≥96.0%; ≥97% (TLC); ≥97.0% (HPLC); ≥99.0% (HPLC)
• Concentration: 20%
• Grade: for molecular biology; SAJ first grade
• Description: anionic
• Impurities: ≤0.01% peroxides; ≤0.1% Insoluble matter; ≤0.1% Phosphorus (P); ≤7% water; DNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected; RNases, none detected
• Cation Traces: Al: ≤0.0005%; Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.01%; Ca: ≤10 mg/kg; Ca: ≤20 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤5 mg/kg; Fe: ≤0.005%; Fe: ≤10 mg/kg; Fe: ≤5 mg/kg; K: ≤0.01%; K: ≤20 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.005%; Mg: ≤10 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH4+: ≤0.05%; Ni: ≤5 mg/kg; Pb: ≤0.01%; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤0.0005%; Zn: ≤5 mg/kg
• Antion Traces: chloride (Cl-): ≤50 mg/kg; sulfate (SO42-): ≤50 mg/kg
• Foreign Activity: DNase, RNase, and protease, none detected; DNase, RNase, none detected
• Loss on Drying: ≤1% loss on drying, 110 °C
• Quality Level: PREMIUM
• Quality: 30% aqueous solution
• Mol. Weight: average mol wt 600; micellar avg mol wt 600
• λ: 1 M in H2O
• Product Line: BioUltra
• Linear Formula: CH3(CH2)10CON(CH3)CH2COONa

DETAILS

Sigma Aldrich - L7414

Features and Benefits
N-Lauroylsarcosine does not precipitate and is commonly used in place of SDS.
General description
For use in hybridization solutions and microarray spotting solutions.

Sigma Aldrich - 61747

Other Notes
Solubilization of membrane proteins; useful for rupturing of eukaryote cells in transcription studies1,2,3; In the lysis of Clostridium perfringens for rapid extraction of plasmids4

Sigma Aldrich - 61743

Other Notes
Anionic surfactant.

Sigma Aldrich - L9150

Application
This salt solution is commonly used in the cell lysis step of RNA purification.
Other Notes
阴离子表面活性剂。

Sigma Aldrich - L5125

Other Notes
阴离子表面活性剂。

Sigma Aldrich - L5777

Other Notes
阴离子表面活性剂。

Sigma Aldrich - 18-0317

Other Notes
Anionic surfactant.

Sigma Aldrich - 61744

Other Notes
Anionic surfactant.
Solubilization and purification of proteins1,2,3; Properties4

Sigma Aldrich - 61745

Other Notes
Anionic surfactant.
Packaging
1 kg in poly bottle
50, 250 g in poly bottle