(1S,2R,10R,11S,14S,15S)-14-hydroxy-14,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one

• ChemBase ID: 128378
• Molecular Formular: C19H28O2
• Molecular Mass: 288.42442
• Monoisotopic Mass: 288.20893014
• SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CCC1=CC(=O)CC[C@H]31
• Canonical SMILES: O=C1CC[C@H]2C(=C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(C)O)C
• InChI: InChI=1S/C19H28O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h11,14-17,21H,3-10H2,1-2H3/t14-,15+,16+,17-,18-,19-/m0/s1
• InChIKey: ZXSWTMLNIIZPET-ZOFHRBRSSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (1S,2R,10R,11S,14S,15S)-14-hydroxy-14,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: matronal
• Synonyms: (17β)-17-Hydroxy-17-methylestr-4-en-3-one; Normethisterone; 13β,17α-Dimethyl-17-hydroxygon-4-en-3-one; 17-Methyl-19-nortestosterone; NSC 10039; RU 598; Normethandrone; 17β-Hydroxy-17α-methylestr-4-en-3-one; 19-Normethisterone; Lutenin; Matronal; Metalutin; Methalutin; Methylestrenolone; Methylnortestosterone; Normetandrone; Normethandrolone; Normethandrone; Normethanedrolone; Orgasteron; Methylestrenolone

Database IDs

• CAS Number: 514-61-4
• PubChem SID: 162222686
• PubChem CID: 5284597
• ATC CODE: G03DC31
• CHEMBL: 269549
• Chemspider ID: 4447645
• Unique Ingredient Identifier: 743F1Z557A
• Wikipedia Title: Methylestrenolone

CALCULATED PROPERTIES

• Acid pKa: 19.278757
• H Acceptors: 2
• H Donor: 1
• LogD (pH = 5.5): 3.3459525
• LogD (pH = 7.4): 3.3459527
• Log P: 3.3459527
• Molar Refractivity: 84.5929 cm^3
• Polarizability: 33.260063 Å^3
• Polar Surface Area: 37.3 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Chloroform; Ethanol; Methanol
• Apperance: White Solid
• Melting Point: 149-151°C

Safety Information

• Storage Condition: Controlled Substance, -20°C Freezer

DETAILS

Toronto Research Chemicals - N734500

Androgen. Controlled substance (anabolic steroid).

REFERENCES

• Death, A., et al.: Steroids, 70, 946 (2000)
• Matias, P., et al.: J. Biol. Chem., 275, 26164 (2000)
• Fang, H., et al.: Chem. Res. Toxicol., 16, 1338 (2000)
• Raudrant, D., et al.: Drugs 63, 463 (2000)