chloro(methoxy)methane

• ChemBase ID: 126533
• Molecular Formular: C2H5ClO
• Molecular Mass: 80.5135
• Monoisotopic Mass: 80.00289246
• SMILES: COCCl
• Canonical SMILES: COCCl
• InChI: InChI=1S/C2H5ClO/c1-4-2-3/h2H2,1H3
• InChIKey: XJUZRXYOEPSWMB-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: chloro(methoxy)methane
• IUPAC Traditional name: chloromethyl methyl ether
• Synonyms: Chlorodimethyl Ether; Chloromethoxymethane; Methoxychloromethane; Monochlorodimethylene Ether; Chloromethyl Methyl Ether, > 90%; MOM-Cl; CMME; Chloromethyl methyl ether; MOM chloride; Methoxymethyl chloride; Methyl chloromethyl ether; Chloromethyl methyl ether; 氯甲氧基甲烷; 甲基氯甲醚; 氯甲基甲醚

Database IDs

• CAS Number: 107-30-2
• EC Number: 203-480-1
• MDL Number: MFCD00000885
• PubChem SID: 162220865; 24846524
• PubChem CID: 7864
• Chemspider ID: 13852893
• KEGG ID: C19160
• Wikipedia Title: Chloromethyl_methyl_ether

CALCULATED PROPERTIES

• H Acceptors: 1
• H Donor: 0
• LogD (pH = 5.5): 0.7383064
• LogD (pH = 7.4): 0.7383064
• Log P: 0.7383064
• Molar Refractivity: 17.6519 cm^3
• Polarizability: 7.0167212 Å^3
• Polar Surface Area: 9.23 Å^2
• Rotatable Bonds: 1
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Chloroform; Methanol
• Apperance: Clear Colourless Oil
• Boiling Point: 328-330 °K, 55-57 °C; 55-57 °C(lit.)
• Flash Point: 16 °C; 60.8 °F
• Density: 1.06 g/mL; 1.06 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.396(lit.)
• Vapor Pressure: 3.55 psi ( 20 °C)

Safety Information

• Storage Condition: Refrigerator
• RTECS: KN6650000
• European Hazard Symbols: Flammable (F); Toxic (T)
• UN Number: 1239
• German water hazard class: 3
• Hazard Class: 6.1
• Packing Group: 1
• Risk Statements: 45-11-20/21/22; R11 R20/21/22 R45
• Safety Statements: 53-45; S45 S53
• GHS Pictograms: GHS02; GHS07; GHS08
• GHS Signal Word: Danger
• GHS Hazard statements: H225-H302 + H312 + H332-H319-H350
• GHS Precautionary statements: P201-P210-P280-P305 + P351 + P338-P308 + P313
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
• RID/ADR: UN 1239 6.1/PG 1
• Storage Temperature: 2-8°C

Product Information

• Grade: technical grade
• Linear Formula: ClCH2OCH3

DETAILS

Sigma Aldrich - 100331

Application
Used to prepare methoxymethyl complexes of Mn and Re coordinated to carbonyl and dipyridyl ligands.1
Useful for the introduction of the methoxymethyl(MOM) protecting group
Packaging
25, 100 g in glass bottle

Toronto Research Chemicals - C369295

A chloroalkyl ether that is an efficient alkylating agent. Used as an alcohol protecting group in the preparation of various organic compounds. A known human carcinogen.

REFERENCES

• Lewis, D.F.V. et al.: Human Exp. Toxicol., 21, 115 (2002)
• Van Duuren, B.L.: Environ. Res., 49, 143 (2002)