sodium tetradecanoate

• ChemBase ID: 111180
• Molecular Formular: C14H27NaO2
• Molecular Mass: 250.35275
• Monoisotopic Mass: 250.19087439
• SMILES: [Na+].CCCCCCCCCCCCCC(=O)[O-]
• Canonical SMILES: CCCCCCCCCCCCCC(=O)[O-].[Na+]
• InChI: InChI=1S/C14H28O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16;/h2-13H2,1H3,(H,15,16);/q;+1/p-1
• InChIKey: JUQGWKYSEXPRGL-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: sodium tetradecanoate
• IUPAC Traditional name: sodium myristate; potassium myristate
• Synonyms: Myristic acid sodium salt; Tetradecanoic acid sodium salt; Sodium myristate; SODIUM MYRISTATE; 十四烷酸 钠盐; 肉豆蔻酸 钠盐

Database IDs

• CAS Number: 822-12-8
• EC Number: 212-487-9
• MDL Number: MFCD00042653
• Beilstein Number: 3575157
• PubChem SID: 162096564; 24886060; 24897209
• PubChem CID: 23693095

CALCULATED PROPERTIES

• Acid pKa: 4.9520197
• H Acceptors: 2
• H Donor: 0
• LogD (pH = 5.5): 4.71164
• LogD (pH = 7.4): 2.9525049
• Log P: 5.3674455
• Molar Refractivity: 78.7187 cm^3
• Polarizability: 26.917377 Å^3
• Polar Surface Area: 40.13 Å^2
• Rotatable Bonds: 12
• Lipinski's Rule of Five: false

PROPERTIES

Safety Information

• German water hazard class: 1
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C

Product Information

• Purity: ≥98.0% (NT); ≥99%
• Linear Formula: CH3(CH2)12COONa

DETAILS

MP Biomedicals - 05218067

MP Biomedicals Rare Chemical collection

Sigma Aldrich - M8005

Biochem/physiol Actions
Myristate (tetradecanoic acid) is a saturated (C14:0) medium-chain fatty acid. Sodium myristate is used in surfactant, cholloidal and hydrophobic/absorption chemistry involving molecules such as proteins.
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease .

Sigma Aldrich - 70140

Application
Sodium myristate was used for the N-myristoylation of recoverin 1.
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.