2-(aminomethyl)-6-[(4,6-diamino-3-{[4-amino-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]oxane-3,4,5-triol; sulfuric acid

• ChemBase ID: 105802
• Molecular Formular: C18H38N4O14S
• Molecular Mass: 566.57772
• Monoisotopic Mass: 566.21052292
• SMILES: NCC1OC(OC2C(N)CC(N)C(OC3CC(N)C(O)C(CO)O3)C2O)C(O)C(O)C1O.OS(=O)(=O)O
• Canonical SMILES: OS(=O)(=O)O.OCC1OC(OC2C(N)CC(C(C2O)OC2OC(CN)C(C(C2O)O)O)N)CC(C1O)N
• InChI: InChI=1S/C18H36N4O10.H2O4S/c19-3-8-12(25)13(26)14(27)18(30-8)32-17-7(22)1-6(21)16(15(17)28)31-10-2-5(20)11(24)9(4-23)29-10;1-5(2,3)4/h5-18,23-28H,1-4,19-22H2;(H2,1,2,3,4)
• InChIKey: KXNGDFWSMYZDOC-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 2-(aminomethyl)-6-[(4,6-diamino-3-{[4-amino-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]oxane-3,4,5-triol; sulfuric acid
• IUPAC Traditional name: 2-(aminomethyl)-6-[(4,6-diamino-3-{[4-amino-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl)oxy]oxane-3,4,5-triol; sulfuric acid
• Synonyms: Kanamycin Sulfate; KANAMYCIN MONOSULFATE; KANAMYCIN MONOSULFATE SALT γ-IRRADIATED; KANAMYCIN MONOSULFATE, USP

Database IDs

• CAS Number: 25389-94-0
• EC Number: 246-933-9
• PubChem SID: 162092611
• PubChem CID: 44134791

CALCULATED PROPERTIES

• Acid pKa: 12.166702
• H Acceptors: 14
• H Donor: 10
• LogD (pH = 5.5): -17.280672
• LogD (pH = 7.4): -12.268114
• Log P: -6.1602755
• Molar Refractivity: 104.6238 cm^3
• Polarizability: 44.58057 Å^3
• Polar Surface Area: 262.38 Å^2
• Rotatable Bonds: 6
• Lipinski's Rule of Five: false

PROPERTIES

Physical Property

• Melting Point: >250°C

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• RTECS: NZ3225030

Product Information

• Grade: USP

DETAILS

MP Biomedicals - 02194531

Cell Culture Reagent
From Streptomyces kanamycetikus Crystalline
Activity: Approx. 735 μg/mg
Acts as an inhibitor of protein biosynthesis by producing a misreading of the 70s-ribosome.

MP Biomedicals - 02194793

From Streptomyces kanamycetikus
γ-Irradiated
Molecular Biology Reagent
Monosulfate Salt
Binds to the 70S subunit; inhibits translocation; elicits coding errors.
Activity: Approx. 735 μg/mg
Acts as an inhibitor of protein biosynthesis by producing a misreading of the 70S-ribosome.