sodium iodide

• ChemBase ID: 105759
• Molecular Formular: INa
• Molecular Mass: 149.89424
• Monoisotopic Mass: 149.89424228
• SMILES: [Na+].[I-]
• Canonical SMILES: [Na+].[I-]
• InChI: InChI=1S/HI.Na/h1H;/q;+1/p-1
• InChIKey: FVAUCKIRQBBSSJ-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: sodium iodide
• IUPAC Traditional name: sodium iodide; potassium iodide
• Synonyms: Sodium iodide; Sodium iodide, ultra dry; Sodium iodide hydrate, Puratronic®; Anayodin; ioduril; SODIUM IODIDE ACS REAGENT GRADE; Sodium iodide; Additive Screening Solution 18/Fluka kit no 78374; Sodium iodide solution; Sodium iodide 1 M solution; Iodide, Ion chromatography standard solution, Specpure®, I? 1000 g/ml; Sodium iodide, ACS; SodiuMiodide; 碘化钠,超干; 碘化钠, 超干; 水合碘化钠, Puratronic®; 碘化钠; 碘盐, 离子色谱标准溶液, Specpure®, I? 1000μg/ml; 碘化钠, ACS

Database IDs

• CAS Number: 7681-82-5
• EC Number: 231-679-3
• MDL Number: MFCD00011355; MFCD00003532
• Merck Index: 148631
• PubChem SID: 24853023; 24867531; 24886254; 24865632; 24863939; 162092579; 24853759; 24845428
• PubChem CID: 5238
• CHEBI ID: 33167
• CHEMBL: 1644695
• Chemspider ID: 5048
• Unique Ingredient Identifier: F5WR8N145C
• Wikipedia Title: Sodium_iodide

CALCULATED PROPERTIES

• Acid pKa: -9.0
• H Acceptors: 0
• H Donor: 0
• LogD (pH = 5.5): 1.2409753
• LogD (pH = 7.4): 1.2409753
• Log P: 1.0205557
• Molar Refractivity: 13.9462 cm^3
• Polarizability: 5.349007 Å^3
• Polar Surface Area: 0.0 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: 178.8 g/100 mL (20 °C) ; 184 g/100 mL (25 °C) ; 294 g/100 mL (70 °C) ; 302 g/100 mL (100 °C) in water; soluble in ethanol and acetone (39.9 g/100 mL); Soluble in water, alcohol, glycerol, acetone. Insoluble in ether
• Apperance: -10 Mesh Beads, Ampouled under argon; beads; crystalline; Crystalline Aggregates; Crystalline Powder; Liquid; Powder; Powder, Ampouled under argon; solid; white solid ; deliquescent
• Melting Point: 651°C; 661 °C(lit.); 661°C
• Boiling Point: 1300-1304°C; 1304°C
• Flash Point: Non-flammable
• Density: 1.11 g/mL at 20 °C; 3.67; 3.67 g/cm^3
• Refractive Index: 1.7745
• Vapor Pressure: 1 mm Hg at 767 °C
• Vapor Density: >1 (vs air)
• pKa: 8-9.5
• Odor: odorless
• Std enthalpy of formation: -288 kJ·mol^-1
• Std molar entropy: 91 J·mol^-1·K^-1
• pH: 6.0-9.0 (25 °C, 5%)

Safety Information

• Storage Condition: Room Temperature (15-30°C), Desiccate
• Storage Warning: Hygroscopic
• RTECS: WB6475000
• European Hazard Symbols: Nature polluting (N); Irritant (Xi)
• German water hazard class: 1
• Risk Statements: 36/37/38; 36/38-50; R:36/37/38
• Safety Statements: 26-37; 26-61; S:20-25-26-37/39
• TSCA Listed: 是
• EU Index: Not listed
• GHS Pictograms: GHS07; GHS09
• GHS Signal Word: Warning
• Main Hazard: Irritant, can harm the unborn child
• GHS Hazard statements: H302-H315-H319-H335; H315-H319; H315-H319-H335; H315-H319-H400
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A; P273-P305 + P351 + P338; P305 + P351 + P338
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves; Eyeshields, Gloves
• Storage Temperature: 2-8°C

Product Information

• Purity: ≥99%; ≥99%; ≥99.0%; ≥99.0% (AT); ≥99.5%; ≥99.99% trace metals basis; 97%; 98%; 99.5% min; 99.9% (metals basis); 99.98% (metals basis); 99.99% (metals basis); 99.999% (metals basis); 99.999% trace metals basis; 99+% (dry wt., water <1.0%); 99-100.5% (calc. to the dried substance)
• Grade: ACS; ACS reagent; anhydrous; puriss.; puriss. p.a.; purum p.a.; REAGENT; reagent grade; ReagentPlus®; SAJ first grade; SAJ special grade
• Particle Size: -10 mesh
• Suitability: complies for appearance of solution; meets USP testing specifications
• Impurities: <1.0% water; <2% water; ≤0.0005% heavy metals (as Pb); ≤0.002% N compounds; ≤0.002% total nitrogen (N); ≤0.003% total nitrogen (N); ≤0.005% thiosulfate (S2O3); ≤0.01% insolubles; ≤0.02% free alkali (as NaOH); ≤2% water (Karl Fischer); alkalic reac. Impurities, complies; barium and thiosulfate, complies; organic volatile impurities, complies (GC); residual solvents, in accordance
• Cation Traces: Ba: ≤0.002%; Ca: ≤0.002%; Ca: ≤10 mg/kg; Ca: ≤50 mg/kg; Cd: ≤1 mg/kg; Cd: ≤50 mg/kg; Co: ≤1 mg/kg; Co: ≤50 mg/kg; Cr: ≤5 mg/kg; Cu: ≤1 mg/kg; Cu: ≤50 mg/kg; Fe: ≤5 mg/kg; Fe: ≤5 ppm; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤5 ppm; K: ≤0.01%; K: ≤50 mg/kg; K: ≤500 mg/kg; Mg: ≤0.001%; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Ni: ≤1 mg/kg; Ni: ≤50 mg/kg; Pb: ≤1 mg/kg; Pb: ≤50 mg/kg; Zn: ≤1 mg/kg; Zn: ≤50 mg/kg
• Antion Traces: bromide, chloride (as Cl-): ≤100 mg/kg; bromide, chloride (as Cl-): ≤200 mg/kg; bromide, chloride (as Cl-): ≤300 mg/kg; Cl- and Br-: ≤0.01%; iodate (IO3-): ≤2 mg/kg; iodate (IO3-): ≤3 ppm; phosphate (PO43-): ≤0.001%; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤100 mg/kg; sulfate (SO42-): ≤150 mg/kg; sulfate (SO42-): ≤50 mg/kg
• Loss on Drying: ≤0.5% loss on drying, 110 °C; ≤2% loss on drying, 105 °C
• Quality: meets analytical specification of Ph. Eur., BP, USP
• Linear Formula: NaI

DETAILS

MP Biomedicals - 02193979

ACS Reagent Grade
Purity: >99%

Sigma Aldrich - 439681

Packaging
5, 25 g in ampule

Sigma Aldrich - 409286

Packaging
1 g in glass bottle
10 g in amber poly
100 g in poly bottle

Sigma Aldrich - 229911

Packaging
10 g in amber poly
100 g in poly bottle

Sigma Aldrich - 217638

Packaging
100, 500 g in poly bottle
2.5 kg in poly bottle
5 g in glass bottle
Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Sigma Aldrich - 03129

Caution
may contain black particle through the manufacture

Sigma Aldrich - 383112

Packaging
100, 500, 6×500 g in poly bottle
12 kg in fiber drum
2.5 kg in poly bottle

REFERENCES

• Converts alkyl chlorides or bromides to iodides (Finkelstein reaction). Preferred solvents are acetone or MEK, in which NaI, but not the chloride or bromide, is soluble. See, e.g.: Org. Synth. Coll., 2, 476 (1955); 4, 84 (1963). Activated aryl halides, such as 1-chloro-2,4-dinitrobenzene can be converted to iodides by reaction with NaI in DMF: Org. Synth. Coll., 5, 478 (1973).
• Frequently used in catalytic amounts to increase the rate of nucleophilic displacement reactions of alkyl halides and sulfonates; see, for example: Org. Synth. Coll., 9, 46 (1998).
• Ethers can be cleaved to ω-iodo esters with a combination of NaI and an acyl chloride: Tetrahedron Lett., 23, 681 (1982). Cleavage of ethers also occurs in the presence of TMS chloride: Angew. Chem. Int. Ed., 20, 690 (1981); J. Org. Chem., 44, 1247 (1979); 48, 3667 (1983). The same combination also reduces benzylic alcohols to arylmethanes: Tetrahedron Lett., 28, 3817 (1987); Bull. Chem. Soc. Jpn., 62, 3537 (1989) and deprotects MEM ethers: Tetrahedron Lett., 25, 1429 (1984); see 2-Methoxyethoxymethyl chloride, L01050.
• In combination with Titanium(IV) chloride, 14713, reduction of amine oxides and nitrones occurs: Chem. Ber., 123, 647 (1990). Similarly, sulfoxides are reduced to sulfides: Synthesis, 155 (1991), and mild reductive deoximation can be effected: Synth. Commun., 21,1777 (1991).