bis(pyridine-2-carbonyloxy)chromio pyridine-2-carboxylate

• ChemBase ID: 105616
• Molecular Formular: C18H12CrN3O6
• Molecular Mass: 418.30048
• Monoisotopic Mass: 418.01311762
• SMILES: O=C(O[Cr](OC(=O)c1ccccn1)OC(=O)c1ccccn1)c1ccccn1
• Canonical SMILES: O=C(c1ccccn1)O[Cr](OC(=O)c1ccccn1)OC(=O)c1ccccn1
• InChI: InChI=1S/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
• InChIKey: CBDQOLKNTOMMTL-UHFFFAOYSA-K

NAMES AND DATABASE IDS

Names

• IUPAC name: bis(pyridine-2-carbonyloxy)chromio pyridine-2-carboxylate
• IUPAC Traditional name: bis(pyridine-2-carbonyloxy)chromio pyridine-2-carboxylate
• Synonyms: 2-Pyridinecarboxylic acid chromium salt; α-picolinic acid chromium salt; Chromium picolinate; PICOLINIC ACID CHROMIUM SALT; Cr(pic)3; CrPic; Chromium picolinate

Database IDs

• CAS Number: 14639-25-9
• MDL Number: MFCD00068715
• PubChem SID: 162092152
• PubChem CID: 625469

CALCULATED PROPERTIES

• H Acceptors: 6
• H Donor: 0
• LogD (pH = 5.5): 1.5317528
• LogD (pH = 7.4): 1.532688
• Log P: 1.5327
• Molar Refractivity: 89.5731 cm^3
• Polarizability: 38.018597 Å^3
• Polar Surface Area: 117.57 Å^2
• Rotatable Bonds: 9
• Lipinski's Rule of Five: true

PROPERTIES

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• RTECS: US5647790
• European Hazard Symbols: Irritant (Xi)
• German water hazard class: 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• GHS Precautionary statements: P261-P305 + P351 + P338
• Storage Temperature: room temp

Product Information

• Purity: ≥98% (HPLC)
• Biological Source: from synthetic
• Loss on Drying: ≤5% loss on drying
• Empirical Formula (Hill Notation): C18H12CrN3O6

DETAILS

MP Biomedicals - 02193542

Chromium Salt

Sigma Aldrich - C4124

Biochem/physiol Actions
Chromium picolinate (CrPic) is a supplemental or alternative medication for type 2 diabetes. Experimental evidence shows the effect of CrPic on glucose uptake through the activation of p38 MAPK.1 Chromium is thought to potentiate the action of insulin, leading to increased insulin sensitivity in type 2 diabetes.2
General description
Chromium picolinate is a supplemental or alternative medication for type 2 diabetes and an anti-diabetic mechanisms of CrPic in insulin-resistant 3T3-L1 adipocytes.