boric acid

• ChemBase ID: 105578
• Molecular Formular: BH3O3
• Molecular Mass: 61.83302
• Monoisotopic Mass: 62.01752436
• SMILES: OB(O)O
• Canonical SMILES: OB(O)O
• InChI: InChI=1S/BH3O3/c2-1(3)4/h2-4H
• InChIKey: KGBXLFKZBHKPEV-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: boric acid
• IUPAC Traditional name: boric acid
• Synonyms: Boric acid, Puratronic®; Boric acid, ACS; Acidum boricum; Boric acid solution; Boron standard for AAS; Boracic Acid; Orthboric Acid; BORIC ACID ACS REAGENT GRADE; BORIC ACID; Boric acid; Orthoboric acid; Sassolite; Optibor; Borofax; Boron atomic spectroscopy standard concentrate 1.000 g B; Boric acid solution; Boron standard solution; 硼酸, Puratronic®; 硼酸, ACS; 硼酸; 硼酸 溶液; 硼原子吸收标准液; 硼酸; 硼原子光谱标准浓缩液 1.000g B; 硼酸 溶液; Boron standard solution

Database IDs

• CAS Number: 10043-35-3
• EC Number: 233-139-2
• MDL Number: MFCD00011337
• Beilstein Number: 1697939
• Merck Index: 141336
• PubChem SID: 24858526; 162092366; 24891517; 24891821; 24891508; 24891666; 24847260; 24892148; 24860608; 24852125; 24891620; 24892029; 24849566; 24849622; 24847262; 24892015
• PubChem CID: 7628
• CHEBI ID: 33118
• CHEMBL: 42403
• Chemspider ID: 7346
• KEGG ID: D01089
• Unique Ingredient Identifier: R57ZHV85D4
• Wikipedia Title: Boric_acid

CALCULATED PROPERTIES

• Acid pKa: 8.698678
• H Acceptors: 3
• H Donor: 3
• LogD (pH = 5.5): -0.5088733
• LogD (pH = 7.4): -0.52978307
• Log P: -0.5086
• Molar Refractivity: 7.6938 cm^3
• Polarizability: 4.730119 Å^3
• Polar Surface Area: 60.69 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: 2.52 g/100 mL (0 °C) ; 4.72 g/100 mL (20 °C) ; 5.7 g/100 mL (25 °C) ; 19.10 g/100 mL (80 °C) ; 27.53 g/100 mL (100 °C) in water; ethanol: in accordance; H2O: soluble; H2O: soluble0.5 M, clear, colorless; H2O: soluble1 M, clear, colorless (hot); Soluble in lower alcohols ; moderately soluble in pyridine ; very slightly soluble in acetone; Soluble in water (1 gram in 18ml cold or 4ml boiling water). Solubility in water is increased by addition of HCl, citric or tartaric acid
• Apperance: +8 Mesh Granular; APHA: ≤10; granular; Granular; powder; Powder; tablet; White crystalline solid
• Melting Point: 160 °C (dec.)(lit.); 168 - 170 °C; 170.9°C; ca 185°C dec.
• Boiling Point: 300 °C; 300°C
• Flash Point: None; Non-flammable.
• Density: 1.435; 1.435 g/cm^3; 1.5172 g/cm^3 at 14 °C
• Vapor Pressure: 2.6 mmHg ( 20 °C)
• Absorption Wavelength: A1M/260, H2O ≤0.05; A1M/280, H2O ≤0.05; λ: 260 nm Amax: 0.015; λ: 280 nm Amax: 0.010
• pKa: 9.24 (see text)
• pH: 3.5-6.0 (0.5 M in H2O); 3.6-4.0 (20 °C, 4%); 3.6-4.4 (25 °C, saturated solution in H2O); 3.8-4.8 (20 °C, 3.3%)

Safety Information

• Storage Condition: Room Temperature (15-30°C); Room Temperature (15-30°C), Desiccate
• RTECS: ED4550000
• European Hazard Symbols: Harmful (Xn); Repr. Cat. 2; Toxic (T); Irritant (Xi)
• German water hazard class: 1; nwg
• Risk Statements: 60-61; R:36/37/38; R60 R61
• Safety Statements: 53-45; S:20-25-26-37/39; S53 S45
• TSCA Listed: 是
• GHS Pictograms: GHS08
• GHS Signal Word: Danger
• NFPA704:
  

  0

  1

  0
• LD50: 2660 mg/kg, oral (rat)
• GHS Hazard statements: H360; H360-H303
• GHS Precautionary statements: P201-P308 + P313; P201-P312-P308+P313
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges; Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Product Information

• Purity: ~99%; ≥99%; ≥99.0% (T); ≥99.5%; ≥99.5% (T); ≥99.5% (titration); ≥99.8%; 4%±0.05%; 98%; 99.5% min; 99.5-100.5%; 99.8%; 99.97% trace metals basis; 99.99% (metals basis); 99.999% trace metals basis; 99.9995% (metals basis); 99+%
• Concentration: 1 mg/mL B; 1.000 g/L B; 1000 ppm B; in H2O
• Grade: ACS; ACS reagent; Biotechnology Performance Certified; for electrophoresis; for ICP; for molecular biology; JIS special grade; Ph Eur; puriss.; puriss. p.a.; purum p.a.; REAGENT; ReagentPlus®; SAJ first grade
• Particle Size: 20-230 mesh
• Suitability: cell culture tested; complies for appearance of solution; plant cell culture tested; suitable for amino acid analysis; suitable for atomic absorption spectrometry; suitable for cell culture; suitable for plant cell culture
• Impurities: <0.05% non-volatile substances in MeOH/HCl; ≤0.001% heavy metals (as Pb); ≤0.005% Insoluble in methanol; ≤0.005% insoluble in methanol; ≤0.005% Phosphorus (P); ≤0.05% non-volatile substances in MeOH/HCl; ≤0.05% Nonvolatile with methanol; ≤0.05% with methanol-HCl non-volat. matter; ≤0.1% Insoluble matter; Bioburden, tested; DNases, none detected; endotoxin, tested; insoluble matter, passes filter test; organic substances, complies; phosphatases, none detected; proteases, none detected; residual solvents, complies; RNases, none detected
• Cation Traces: Ag: ≤0.05 mg/kg; Al: ≤0.0005%; Al: ≤0.1 mg/kg; Al: ≤5 mg/kg; As: ≤0.5 mg/kg; As: ≤5 mg/kg; Ba: ≤0.05 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.005%; Ca: ≤0.1 mg/kg; Ca: ≤10 mg/kg; Ca: ≤20 mg/kg; Ca: ≤50 mg/kg; Cd: ≤0.05 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Co: ≤0.05 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤0.05 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤0.1 mg/kg; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Fe: ≤0.0005%; Fe: ≤0.001%; Fe: ≤0.05 mg/kg; Fe: ≤1 mg/kg; Fe: ≤5 mg/kg; Fe: ≤5 ppm; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤0.001%; heavy metals (as Pb): ≤10 ppm; K: ≤0.005%; K: ≤100 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.005%; Mg: ≤0.05 mg/kg; Mg: ≤5 mg/kg; Mg: ≤5 ppm; Mn: ≤0.05 mg/kg; Mn: ≤5 mg/kg; Mo: ≤0.05 mg/kg; Mo: ≤5 mg/kg; Na: ≤0.01%; Na: ≤100 mg/kg; Na: ≤50 mg/kg; NH4+: ≤0.05%; Ni: ≤0.1 mg/kg; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤0.001%; Pb: ≤0.1 mg/kg; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Sn: ≤0.1 mg/kg; Sr: ≤0.05 mg/kg; Sr: ≤5 mg/kg; Ti: ≤0.05 mg/kg; V: ≤0.05 mg/kg; Zn: ≤0.0005%; Zn: ≤0.05 mg/kg; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg; Zr: ≤0.05 mg/kg
• Antion Traces: chloride (Cl-): ≤0.001%; chloride (Cl-): ≤0.05%; chloride (Cl-): ≤3 mg/kg; chloride (Cl-): ≤5 mg/kg; chloride (Cl-): ≤50 mg/kg; phosphate (PO43-): ≤0.001%; phosphate (PO43-): ≤5 mg/kg; sulfate (SO42-): ≤0.01%; sulfate (SO42-): ≤0.05%; sulfate (SO42-): ≤200 mg/kg; sulfate (SO42-): ≤400 mg/kg; sulfate (SO42-): ≤5 mg/kg
• Foreign Activity: DNase, RNase, and protease, none detected; DNase, RNase, Protease, none detected
• Shelf Life: (limited shelf life, expiry date on the label)
• Loss on Drying: ≤0.5% loss on drying, 20 °C (HV); ≤0.5% loss on drying, 5 h (on silica gel)
• Quality: ampule; meets analytical specification of Ph. Eur., BP, NF
• λ: 1 M in H2O
• Product Line: BioUltra
• Linear Formula: H3BO3

DETAILS

MP Biomedicals - 02194810

Molecular Biology Reagent
Purity: ~99%
Fe: =5 ppm

MP Biomedicals - 02191411

ACS Reagent Grade
Crystalline

Sigma Aldrich - 15663

Other Notes
Running buffer component with methylmercuric hydroxide gels1; Buffer component in DNA digest analysis with capillary electrophoresis2
Application
Boric acid can be used to study molecular biology, DNA and RNA purification, biological buffers and molecular biology reagents. Boric acid has been used to test the toxic effects of boron on growth and antioxidant system parameters of maize (Zea mays L.) roots. Boric acid has also been used to study the effect of time period after boric acid injection on (10)B absorption in different regions of adult male rat′s brain.

Sigma Aldrich - B2645

Quantity
每片含 1g 硼酸。

Sigma Aldrich - 15579

Preparation Note
prepared with B(OH)3 and H2O

Sigma Aldrich - 416711

Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Sigma Aldrich - 15670

Other Notes
Catalyst for the decarboxylation of malonic esters1

Sigma Aldrich - 15665

Other Notes
Calibration of polyacrylamide gel columns for the separation of oligonucleotides by capillary electrophoresis1

Sigma Aldrich - 202878

Packaging
10, 50, 250 g in poly bottle

Sigma Aldrich - B0252

包装
1, 2.5 kg in poly bottle
5, 10 kg in poly drum
500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 339067

Packaging
100, 500 g in poly bottle

Sigma Aldrich - B0394

包装
1 kg in poly bottle
100, 500 g in poly bottle
5, 12 kg in poly drum

REFERENCES

• Promotes the decarboalkoxylation of malonic esters and analogous compounds: Synth. Commun., 9, 609 (1979); Org. Synth. Coll., 6, 615 (1988); Can. J. Chem., 69, 1201 (1991).
• Catalyzes the N-acylation of indoles with carboxylic acids: Heterocycles, 19, 91 (1982). Promotes the reaction between Benzenesulfinic acid sodium salt, A12118, and propiolate esters, under phase-transfer conditions, to give (Z)-vinyl sulfones: Org. Synth. Coll., 8, 458 (1993).