(2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

• ChemBase ID: 103675
• Molecular Formular: C12H22O11
• Molecular Mass: 342.29648
• Monoisotopic Mass: 342.11621152
• SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]1([C@H]([C@@H]([C@H](O1)CO)O)O)CO)O)O)O)O
• Canonical SMILES: OC[C@H]1O[C@@]([C@H]([C@@H]1O)O)(CO)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O
• InChI: InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
• InChIKey: CZMRCDWAGMRECN-UGDNZRGBSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
• IUPAC Traditional name: sucrose
• Synonyms: Saccharum; Saccharose; α-D-glucopyranosyl-(1→2)-β-D-fructofuranoside;β-D-fructofuranosyl-(2→1)-α-D-glucopyranoside; β-(2S,3S,4S,5R)-fructofuranosyl-α-(1R,2R,3S,4S,5R)-glucopyranoside; α-(1R,2R,3S,4S,5R)-glucopyranosyl-β-(2S,3S,4S,5R)-fructofuranoside; α-D-Glc-(1→2)-β-D-Fru; Sucrose; SUCROSE ULTRA PURE; α-D-Glucopyranosyl β-D-fructofuranoside; β-D-Fructofuranosyl-α-D-glucopyranoside; D(+)-Saccharose; Sugar; β-D-Fructofuranosyl-α-D-glucopyranoside; α-D-Glucopyranosyl β-D-fructofuranoside; SUCROSE, ACS; SUCROSE; 蔗糖; α-D-吡喃葡萄糖基β-D-呋喃果糖苷; β-D-呋喃果糖基-α-D-吡喃葡萄苷; D(+)-蔗糖; 白糖; 蔗糖

Database IDs

• CAS Number: 57-50-1
• EC Number: 200-334-9
• MDL Number: MFCD00006626
• Beilstein Number: 90825
• PubChem SID: 24899574; 24899521; 24870841; 24899501; 162090425; 24899632; 24899423; 24888177; 24899465; 24849903; 24888178; 24899835; 24899768; 24899651; 24899652; 24899793
• PubChem CID: 5988
• CHEBI ID: 17992
• CHEMBL: 253582
• Chemspider ID: 5768
• DrugBank ID: DB02772
• Unique Ingredient Identifier: C151H8M554
• Wikipedia Title: Sucrose

CALCULATED PROPERTIES

• Acid pKa: 11.84128
• H Acceptors: 11
• H Donor: 8
• LogD (pH = 5.5): -4.5288353
• LogD (pH = 7.4): -4.5288506
• Log P: -4.528835
• Molar Refractivity: 68.7741 cm^3
• Polarizability: 28.969793 Å^3
• Polar Surface Area: 189.53 Å^2
• Rotatable Bonds: 5
• Lipinski's Rule of Five: false

PROPERTIES

Physical Property

• Solubility: 2000 g/L (25 °C) in water; H2O: soluble0.1 g/mL; H2O: soluble0.1 g/mL, clear, colorless; H2O: soluble0.5 g/mL, clear, colorless; H2O: soluble0.5 g/mL, clear, faintly yellow; H2O: soluble1 M at 20 °C, clear, colorless; H2O: soluble1 M, clear, colorless; H2O: soluble500 mg/mL
• Apperance: Powder; white solid
• Melting Point: 160-186 °C (320-367 °F) (decomposes). Also reported as 190-192 °C (374-377.6 °F) (decomposes).; 185-187 °C(lit.); 186 °C decomp.
• Density: 1.587 at 25 °C (water = 1); 1.587 g/cm^3, solid
• Vapor Pressure: Not applicable
• Partition Coefficient: -3.76
• Optical Rotation: [α]20/546 +78.0±1°, c = 10 in H2O(lit.); [α]20/D +66.3 to +67.0°, c = 26% in H2O; [α]20/D +66.5±1°, c = 10 in H2O(lit.); [α]20/D +66.5±1°, c = 26% in H2O; [α]20/D 66.3 to 66.8°, c = 26% in H2O; [α]24/D +66.5°, c = 26 in H2O; [α]25/D +66.3 to +66.8°(lit.)
• Absorption Wavelength: A1M/260, H2O ≤0.09; A1M/280, H2O ≤0.06; A50%/260 ≤0.15; A50%/280 <0.15; A50%/280 ≤0.15; λ: 260 nm Amax: 0.11; λ: 280 nm Amax: 0.08
• Conductivity: ≤35 μS/cm
• pH: 5.0-7.0 (25 °C, 1 M in H2O); 5.5-7.0 (25 °C, 1 M in H2O); 5.5-7.5 (20 °C, 1 M in H2O)

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• RTECS: WN6500000
• German water hazard class: 2
• EU Index: not listed
• NFPA704:
  

  1

  1

  0
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Product Information

• Purity: ≥99%; >99%; ≥98.0% (HPLC); ≥99.0%; ≥99.0% (HPLC); ≥99.5%; ≥99.5% (GC); ≥99.5% (HPLC); 99.9%
• Grade: ACS; ACS reagent; analytical standard; for biotechnological purposes; for electrophoresis; for microbiology; for molecular biology; JIS special grade; Ph Eur; puriss.; REAGENT; reagent grade; SAJ first grade
• Packaging: pkg of 500 mg
• Suitability: complies for appearance of solution; insect cell culture tested; meets USP testing specifications; plant cell culture tested; suitable for cell culture; suitable for insect cell culture
• Ignition Residue: ≤0.01%; ≤0.01% (as SO4)
• Impurities: ≤0.0005% heavy metals (as Pb); ≤0.0008 meq/g free acid; ≤0.0008 meq/g Titratable acid; ≤0.005% Insoluble matter; ≤0.005% water insoluble matter; ≤0.05% Invert sugar; ≤0.05% invert sugar; ≤0.1% free glucose; ≤250 EU/g endotoxins (LAL test); ≤5 mg/kg heavy metals (as Pb); acidity or alkalinity, complies; dextrine, complies; DNases, none detected; Insoluble matter, passes filter test; insoluble matter, passes filter test; invert sugar, complies; organic volatile impurities, in accordance (GC); phosphatases, none detected; proteases, none detected; reducing sugar, complies; residual solvents, complies; RNases, none detected
• Cation Traces: Al: ≤0.0005%; Al: ≤5 mg/kg; As: ≤0.0001%; As: ≤0.1 mg/kg; Ba: ≤0.0005%; Ba: ≤5 mg/kg; Bi: ≤0.0005%; Bi: ≤5 mg/kg; Ca: ≤0.001%; Ca: ≤10 mg/kg; Ca:, in accordance; Cd: ≤0.0005%; Cd: ≤5 mg/kg; Co: ≤0.0005%; Co: ≤5 mg/kg; Cr: ≤0.0005%; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤5 mg/kg; Fe: ≤0.0005%; Fe: ≤5 mg/kg; Fe: ≤5 ppm; heavy metals (as Pb): <5 ppm; heavy metals (as Pb): ≤5 ppm; K: ≤0.005%; K: ≤50 mg/kg; Li: ≤0.0005%; Li: ≤5 mg/kg; Mg: ≤0.0005%; Mg: ≤5 mg/kg; Mn: ≤0.0005%; Mn: ≤5 mg/kg; Mo: ≤0.0005%; Mo: ≤5 mg/kg; Na: ≤0.005%; Na: ≤50 mg/kg; Ni: ≤0.0005%; Ni: ≤5 mg/kg; Pb: ≤0.0005%; Pb: ≤0.5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤0.0005%; Sr: ≤5 mg/kg; Zn: ≤0.0005%; Zn: ≤5 mg/kg
• Antion Traces: chloride (Cl-): ≤0.005%; chloride (Cl-): ≤30 mg/kg; chloride (Cl-): ≤50 mg/kg; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤50 mg/kg; sulfate (SO42-): ≤60 mg/kg; sulfate, sulfite (as SO42-): ≤0.005%; sulfate, sulfite (as SO42-): ≤50 mg/kg; sulfite (SO32-): ≤10 mg/kg
• Foreign Activity: DNase, RNase, protease, none detected; RNase, none detected
• Loss on Drying: ≤0.03% loss on drying, 105 °C; ≤0.03% loss on drying, 105°C; ≤0.1% loss on drying, 105 °C, 3 h; ≤0.1% loss on drying, 20 °C (HV); ≤0.2% loss on drying, HV, 18 - 26°C
• Type: Grade I; Grade II
• Quality Level: PREMIUM
• Quality: meets analytical specification of Ph. Eur., BP, NF
• λ: 1 M in H2O
• Pharmacopeia: testing & handling conforms to Pharmacopeia
• Product Line: BioUltra
• Pharmacopeia Traceability: traceable to PhEur S1600000; traceable to USP 1623637
• Color index: ≤45
• Empirical Formula (Hill Notation): C12H22O11

DETAILS

MP Biomedicals - 02152584

ACS Reagent Grade

MP Biomedicals - 04821721

Purity: 99.9% RNase-Free Heavy metals (as Pb): <5 ppm Glucose: <0.1% Arsenic: <0.001 ppm DNAse and RNAse-free.

MP Biomedicals - 04821713

Purity: 99.9% RNase-Free Heavy metals (as Pb): <5 ppm Glucose: <0.1% Arsenic: <0.001 ppm DNAse and RNAse-free.

MP Biomedicals - 02902978

Crystalline
This is a slightly less pure sucrose than our 190271. It does not reduce Fehling's solution, and is suitable for most routine applications.

MP Biomedicals - 02194018

Molecular Biology Reagent
Purity: 99+%
Glucose: <0.1%
Heavy metals (Pb): <5 ppm
DNase, RNase, and protease-free.

MP Biomedicals - 02190271

Crystalline
Suitable for density gradient studies with RNA. Forms a clear colorless solution at a concentration of 5 gm per 10 ml of water.
Heavy metal: <0.0005%

MP Biomedicals - 02194747

Cell Culture Reagent
Crystalline

Sigma Aldrich - S8501

包装
5, 10 kg in poly drum

Sigma Aldrich - S1888

Application
用于为病毒和蛋白的纯化创建蔗糖梯度。

Sigma Aldrich - S5390

Application
用于为病毒和蛋白的纯化创建蔗糖梯度。

Sigma Aldrich - S5016

包装
1 kg in poly bottle
2.5 kg in poly drum
25, 500 g in poly bottle

Sigma Aldrich - S9378

包装
1 kg in poly bottle
10 mg in autosmp vl
5, 10 kg in poly drum
500 g in poly bottle

Sigma Aldrich - S1174

Application
蔗糖测定试剂盒标准品

Sigma Aldrich - 84097

Other Notes
Isopycnic centrifugation in a discontinuous sucrose density gradient e.g. in the isolation of mRNA from membrane-bound polysomes1
Application
Sucrose is a widely used nutitional disaccharide of glucose and fructose. Sucrose is used in molecular biology for the preparation of density gradients.

Sigma Aldrich - S5391

Application
在植物细胞培养应用中用作冷冻保护剂。
Other Notes
纯度略低于 I 级

Sigma Aldrich - 84099

Other Notes
In density gradient centrifugation1,2,3

Sigma Aldrich - 179949

Packaging
1 kg in poly bottle
5 kg in poly drum