acridine hydrochloride

• ChemBase ID: 103001
• Molecular Formular: C13H10ClN
• Molecular Mass: 215.6782
• Monoisotopic Mass: 215.05017701
• SMILES: Cl.c1ccc2nc3ccccc3cc2c1
• Canonical SMILES: c1ccc2c(c1)nc1c(c2)cccc1.Cl
• InChI: InChI=1S/C13H9N.ClH/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12;/h1-9H;1H
• InChIKey: XUESTGHCVFYOLL-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: acridine hydrochloride
• IUPAC Traditional name: acridine hydrochloride
• Synonyms: Acridine Monohydrochloride; Acridinium Chloride; ACRIDINE HYDROCHLORIDE; acridin-10-ium chloride; Acridine hydrochloride

Database IDs

• CAS Number: 17784-47-3
• EC Number: 241-762-6
• MDL Number: MFCD00035149
• Beilstein Number: 3697519
• PubChem SID: 24844900; 162090252
• PubChem CID: 2849400

CALCULATED PROPERTIES

• H Acceptors: 1
• H Donor: 0
• LogD (pH = 5.5): 2.8052485
• LogD (pH = 7.4): 3.4829233
• Log P: 3.5062275
• Molar Refractivity: 56.0575 cm^3
• Polarizability: 24.767927 Å^3
• Polar Surface Area: 12.89 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: H2O: soluble; methanol: soluble
• Melting Point: 236-250°C; 250-255 °C (dec.)

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• RTECS: AR9322000
• European Hazard Symbols: Irritant (Xi); Harmful (Xn)
• German water hazard class: 3
• Risk Statements: 36/37/38; R:20/21/22-36/37/38-40
• Safety Statements: 26-36; S:20-25-26-37/39-45
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• GHS Precautionary statements: P261-P305 + P351 + P338
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves

Product Information

• Purity: ≥90% (AT)
• Grade: for fluorescence
• Suitability: in accordance for fluorescence
• Impurities: ~5% water
• Empirical Formula (Hill Notation): C13H9N · HCl

DETAILS

MP Biomedicals - 02150253

Hydrochloride

Sigma Aldrich - 01645

Application
Acridine hydrochloride is a fluorescent compound with λexcitation and λemission of 355 nm and 440 nm, respectively. To investigate the release properties of multilayer nanocapsules, acridine hydrochloride has been utilized as a hydrophilic drug model and was loaded into the nano-structures 1.