N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)decanamide

• ChemBase ID: 102953
• Molecular Formular: C17H35NO6
• Molecular Mass: 349.4629
• Monoisotopic Mass: 349.24643785
• SMILES: CCCCCCCCCC(=O)N(C)CC(O)C(O)C(O)C(O)CO
• Canonical SMILES: CCCCCCCCCC(=O)N(CC(C(C(C(CO)O)O)O)O)C
• InChI: InChI=1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3
• InChIKey: UMWKZHPREXJQGR-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)decanamide
• IUPAC Traditional name: N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)decanamide
• Synonyms: Decanoyl-N-methylglucamide; N-(D-Glucityl)-N-methyldecanamide; MEGA-10; N-Decanoyl-N-methyl-D-glucamine; MEGA-10; N-Decanoyl-N-methylglucamine

Database IDs

• CAS Number: 85261-20-7
• MDL Number: MFCD00036801
• Beilstein Number: 6974359
• PubChem SID: 24894017; 162089375
• PubChem CID: 5076631

CALCULATED PROPERTIES

• Acid pKa: 12.646883
• H Acceptors: 6
• H Donor: 5
• LogD (pH = 5.5): 0.018136572
• LogD (pH = 7.4): 0.018136043
• Log P: 0.018138526
• Molar Refractivity: 91.2355 cm^3
• Polarizability: 36.41477 Å^3
• Polar Surface Area: 121.46 Å^2
• Rotatable Bonds: 14
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: H2O: soluble10 mg/mL at 20 °C, clear, colorless
• Melting Point: 91-93 °C
• Critical Micelle Concentration: 6-7 mM(20-25°C)

Safety Information

• Storage Condition: 0°C
• German water hazard class: 3
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C

Product Information

• Purity: ~98%; ≥98% (GC); ≥98.0% (TLC)
• Description: non-ionic
• Cation Traces: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤10 mg/kg; Mn: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• Loss on Drying: ≤0.5% loss on drying
• Empirical Formula (Hill Notation): C17H35NO6

DETAILS

MP Biomedicals - 02150057

Purity: ~98%
A nonionic detergent, transparent in UV region. Excellent for use as a membrane protein solubilizer.

Sigma Aldrich - D6277

Application
Non-ionic, dialyzable detergent used for the solubilization of membrane proteins

Sigma Aldrich - 30625

Other Notes
Water soluble detergent with high solubilizing power and non-denaturing properties that can be readily removed by dialysis.; Does not interfere with the monitoring of proteins at 280 nm1