(2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid hydrochloride

• ChemBase ID: 102827
• Molecular Formular: C9H12ClNO3
• Molecular Mass: 217.64948
• Monoisotopic Mass: 217.05057093
• SMILES: Cl.N[C@@H](Cc1ccc(O)cc1)C(=O)O
• Canonical SMILES: OC(=O)[C@H](Cc1ccc(cc1)O)N.Cl
• InChI: InChI=1S/C9H11NO3.ClH/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;/h1-4,8,11H,5,10H2,(H,12,13);1H/t8-;/m0./s1
• InChIKey: JJWFIVDAMOFNPS-QRPNPIFTSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid hydrochloride
• IUPAC Traditional name: L-tyrosine hydrochloride
• Synonyms: L-TYROSINE HYDROCHLORIDE; L-Tyrosine hydrochloride; 3-(4-Hydroxyphenyl)-L-alanine hydrochloride; 3-(4-Hydroxyphenyl)-L-alanine; 3-(4-羟基苯基)-L-丙氨酸; L-苯酚氨基丙酸 盐酸盐; L-酪氨酸 盐酸盐

Database IDs

• CAS Number: 16870-43-2
• MDL Number: MFCD00012617
• PubChem SID: 24900004; 162090089; 24900008
• PubChem CID: 12209702

CALCULATED PROPERTIES

• Acid pKa: 1.9998473
• H Acceptors: 4
• H Donor: 3
• LogD (pH = 5.5): -1.4884841
• LogD (pH = 7.4): -1.495157
• Log P: -1.488594
• Molar Refractivity: 47.0972 cm^3
• Polarizability: 18.512522 Å^3
• Polar Surface Area: 83.55 Å^2
• Rotatable Bonds: 3
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Melting Point: 239 °C (dec.)(lit.); 239°C (dec.)
• Optical Rotation: [α]20/D -8°, c = 4 in 1 M HCl

Safety Information

• Storage Condition: 0°C; Room Temperature (15-30°C)
• European Hazard Symbols: Irritant (Xi)
• German water hazard class: 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• GHS Precautionary statements: P261-P305 + P351 + P338
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves

Pharmacology Properties

• Gene Information: human ... GRIN2C(2905)mouse ... GRIN2C(14813)rat ... GRIN2C(24411)

Product Information

• Purity: ≥98% (TLC); 99%
• Suitability: suitable for cell culture
• Linear Formula: HOC6H4CH2CH(NH2)CO2H·HCl

DETAILS

MP Biomedicals - 02103192

Hydrochloride
Crystalline

MP Biomedicals - 02194760

Cell Culture Reagent
Hydrochloride
Crystalline

Sigma Aldrich - T2025

Other Notes
多巴胺和其他儿茶酚胺的氨基酸前体
General description
Tyrosine is a polar, non-essential amino acid with a phenolic functionality. L-tyrosine is a natural amino acid that is incorporated into proteins as directed by the genetic code. The phenolic function makes the tyrosine residue in proteins a principle recipient of reactions such as phosphorylation/dephosphorylation important for cell signalling. Tyrosine is also a precursor of various neurotransmitters and hormones.

Sigma Aldrich - T2006

Other Notes
多巴胺和其他儿茶酚胺的氨基酸前体
包装
1, 5, 10 g in poly bottle

Sigma Aldrich - 287369

Other Notes
Amino acid precursor of dopamine and other catecholamines