(4-aminobutyl)(3-aminopropyl)amine trihydrochloride

• ChemBase ID: 102175
• Molecular Formular: C7H22Cl3N3
• Molecular Mass: 254.62868
• Monoisotopic Mass: 253.08793076
• SMILES: Cl.Cl.Cl.NCCCCNCCCN
• Canonical SMILES: NCCCNCCCCN.Cl.Cl.Cl
• InChI: InChI=1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
• InChIKey: LCNBIHVSOPXFMR-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (4-aminobutyl)(3-aminopropyl)amine trihydrochloride
• IUPAC Traditional name: spermidine trihydrochloride
• Synonyms: Spermidine trihydrochloride; N1-(3-Aminopropyl)butane-1,4-diamine trihydrochloride; N-(3-Aminopropyl)-1,4-Butanediamine trihydrochloride; SPERMIDINE TRIHYDROCHLORIDE; 亚精胺 三盐酸盐

Database IDs

• CAS Number: 334-50-9
• EC Number: 206-379-0
• MDL Number: MFCD00012918
• Beilstein Number: 3552356
• PubChem SID: 162089581; 24888218; 24277993
• PubChem CID: 9539

CALCULATED PROPERTIES

• H Acceptors: 3
• H Donor: 3
• LogD (pH = 5.5): -10.062785
• LogD (pH = 7.4): -7.799325
• Log P: -1.1495639
• Molar Refractivity: 44.9684 cm^3
• Polarizability: 18.22489 Å^3
• Polar Surface Area: 64.07 Å^2
• Rotatable Bonds: 7
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: H2O: soluble1 M at 20 °C, clear, colorless
• Melting Point: 250-263°C; 257-259 °C(lit.)
• Absorption Wavelength: λ: 260 nm Amax: 0.2; λ: 280 nm Amax: 0.1
• pH: 3.0-6.0 (25 °C, 1 M in H2O)

Safety Information

• Storage Condition: 0°C, Desiccate
• RTECS: EJ7023000
• European Hazard Symbols: Irritant (Xi)
• UN Number: 1759
• German water hazard class: 3
• Hazard Class: 8
• Packing Group: II
• Australian Hazchem: 2X
• Risk Statements: 36/37/38; R:36/37/38
• Safety Statements: 26-36; S:20-25-26-37/39
• EU Classification: C10
• EU Hazard Identification Number: 8B
• Emergency Response Guidebook(ERG) Number: 154
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• GHS Precautionary statements: P261-P305 + P351 + P338
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Storage Temperature: 2-8°C; room temp

Pharmacology Properties

• Gene Information: human ... NOS1(4842)

Product Information

• Purity: ≥98% (TLC); ≥99.5% (AT); 95+%; 99%
• Impurities: insoluble matter, passes filter test
• Cation Traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• λ: 1 M in H2O
• Product Line: BioXtra
• Linear Formula: NH2(CH2)3NH(CH2)4NH2 · 3HCl

DETAILS

MP Biomedicals - 02100472

Crystalline Purity: 99%
Forms stable compounds with nucleic acids.

Sigma Aldrich - S125

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Sigma Aldrich - S2501

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
包装
1, 5, 25 g in poly bottle
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Sigma Aldrich - 85578

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Other Notes
Buffer component for chromosome isolation in bivariate flow cytogenetic analysis and sorting1.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Sigma Aldrich - 233994

Caution
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
Packaging
5 g in glass bottle
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.